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Repligen Corporation (RGEN)

Upturn stock ratingUpturn stock rating
$122.17
Last Close (24-hour delay)
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PASS
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Upturn Advisory Summary

08/28/2025: RGEN (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

19 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $179.72

1 Year Target Price $179.72

Analysts Price Target For last 52 week
$179.72 Target price
52w Low $102.97
Current$122.17
52w High $182.52

Analysis of Past Performance

Type Stock
Historic Profit -30.55%
Avg. Invested days 26
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/28/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 6.88B USD
Price to earnings Ratio -
1Y Target Price 179.72
Price to earnings Ratio -
1Y Target Price 179.72
Volume (30-day avg) 19
Beta 1.05
52 Weeks Range 102.97 - 182.52
Updated Date 08/29/2025
52 Weeks Range 102.97 - 182.52
Updated Date 08/29/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.24

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -2.05%
Operating Margin (TTM) 5.28%

Management Effectiveness

Return on Assets (TTM) 1.13%
Return on Equity (TTM) -0.68%

Valuation

Trailing PE -
Forward PE 73.53
Enterprise Value 6850202191
Price to Sales(TTM) 10.21
Enterprise Value 6850202191
Price to Sales(TTM) 10.21
Enterprise Value to Revenue 10.16
Enterprise Value to EBITDA 68.84
Shares Outstanding 56257600
Shares Floating 52655443
Shares Outstanding 56257600
Shares Floating 52655443
Percent Insiders 6.4
Percent Institutions 104.79

ai summary icon Upturn AI SWOT

Repligen Corporation

stock logo

Company Overview

overview logo History and Background

Repligen Corporation was founded in 1981. It initially focused on developing recombinant protein A and has since evolved into a leading provider of bioprocessing technologies and solutions. Key milestones include strategic acquisitions and product innovations in chromatography, filtration, and process analytics.

business area logo Core Business Areas

  • Filtration: Provides filtration products and systems used in biomanufacturing processes for purification and concentration of biological products.
  • Chromatography: Offers chromatography products, including resins and systems, used for separating and purifying biomolecules.
  • Process Analytics: Develops and supplies process analytics tools and sensors that monitor and control critical parameters in bioprocessing.
  • Cell Culture: Provides cell culture products used in bioprocessing for the development of cell lines and generation of biological products.

leadership logo Leadership and Structure

Tony J. Hunt is the President and CEO. The company has a typical corporate structure with departments focused on R&D, manufacturing, sales, and marketing, reporting to the executive leadership team.

Top Products and Market Share

overview logo Key Offerings

  • OPUS(R) Pre-packed Columns: Pre-packed chromatography columns used for purification of proteins and other biomolecules. Repligen has a significant market share in this segment. Competitors include Cytiva (formerly GE Healthcare Life Sciences) and Bio-Rad Laboratories. Revenue from OPUS is a significant contributor to overall sales.
  • KrosFlo(R) Filtration Systems: Tangential flow filtration (TFF) systems used for separation and purification of biomolecules. Repligen is a key player. Competitors include Sartorius Stedim Biotech and Danaher Corporation (Pall Life Sciences). Revenue from KrosFlo systems is significant in overall sales.
  • NovaSeptum(R) Sampling Systems: Sterile sampling systems used in bioprocessing for monitoring and control. Repligen has a growing market presence. Competitors include Sartorius Stedim Biotech. Revenue for NovaSeptum contributes to process analytics sales.

Market Dynamics

industry overview logo Industry Overview

The bioprocessing industry is experiencing strong growth driven by increasing demand for biologics, biosimilars, and cell and gene therapies. Technological advancements and regulatory requirements are key drivers.

Positioning

Repligen is positioned as a leading provider of bioprocessing solutions, with a focus on innovation, quality, and customer service. Its competitive advantages include a broad product portfolio, strong technical expertise, and established relationships with key customers.

Total Addressable Market (TAM)

The TAM for bioprocessing technologies is estimated to be billions of dollars annually. Repligen is well-positioned to capture a significant share of this market due to its strong product portfolio and market presence.

Upturn SWOT Analysis

Strengths

  • Strong product portfolio
  • Leading market position in key segments
  • Innovative technology
  • Established customer relationships
  • Experienced management team

Weaknesses

  • Dependence on the biopharmaceutical industry
  • Competition from larger players
  • Potential for product recalls
  • Integration risks associated with acquisitions

Opportunities

  • Expanding into new geographic markets
  • Developing new products and technologies
  • Acquiring complementary businesses
  • Capitalizing on the growth of cell and gene therapy

Threats

  • Economic downturn
  • Changes in regulations
  • Increased competition
  • Technological obsolescence

Competitors and Market Share

competitor logo Key Competitors

  • Cytiva
  • Sartorius Stedim Biotech
  • Danaher (Pall Life Sciences)
  • Thermo Fisher Scientific

Competitive Landscape

Repligen has a strong competitive position due to its specialized product portfolio and focus on bioprocessing. However, it faces competition from larger, more diversified companies.

Major Acquisitions

Phenomenex

  • Year: 2023
  • Acquisition Price (USD millions): 775
  • Strategic Rationale: Expanded Repligen's chromatography portfolio and strengthened its presence in the bioprocessing market.

Growth Trajectory and Initiatives

Historical Growth: Repligen has experienced significant revenue growth in recent years, driven by strong demand for its products and strategic acquisitions.

Future Projections: Future growth projections vary based on analyst estimates and market conditions.

Recent Initiatives: Recent initiatives include product launches, acquisitions of complementary businesses, and expansion into new geographic markets.

Summary

Repligen is a strong player in the bioprocessing market, driven by its innovative products and strategic acquisitions. The company's focus on cell and gene therapy presents a significant opportunity. Repligen needs to navigate competition from larger players and manage integration risks from acquisitions. Overall, Repligen shows great potential for continued growth. However, economic downturns could impact the company's growth prospects.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Filings
  • Industry Reports
  • Analyst Estimates

Disclaimers:

The information provided is for informational purposes only and should not be considered financial advice. Market share data is approximate and based on available information. The AI-based rating is subjective and should be used as one factor in investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Repligen Corporation

Exchange NASDAQ
Headquaters Waltham, MA, United States
IPO Launch date 1990-03-26
President, CEO & Director Mr. Olivier Loeillot
Sector Healthcare
Industry Medical Instruments & Supplies
Full time employees 1778
Full time employees 1778

Repligen Corporation, a life sciences company, develops and commercializes bioprocessing technologies and systems in North America, Europe, the Asia Pacific, and internationally. It offers Protein A ligands that are the binding components of Protein A affinity chromatography resins; and cell culture growth factor products. The company also provides chromatography products, including OPUS pre-packed chromatography columns, which are used in the purification of biologics; and OPUS smaller-scale columns that are used in the high throughput process development screening, viral clearance validation studies, and scale down validation of chromatography processes, as well as ELISA test kits. In addition, it offers filtration products, such as XCell ATF Cell Retention Systems that are filtration devices used in upstream perfusion and cell culture processing; TangenX flat sheet cassettes, which are used in downstream biologic drug concentration, buffer exchange, and formulation processes; KrosFlo tangential flow filtration and tangential flow depth filtration systems; and ProConnex TFDF flow paths. Further, it provides process analytics products, such as slope spectroscopy systems under the SoloVPE, FlowVPE, and FlowVPX brands. The company sells its products to life sciences, biopharmaceutical, and diagnostics companies; laboratory researchers; and contract manufacturing organizations. Repligen Corporation has a collaboration agreement with Navigo Proteins GmbH to develop multiple affinity ligands. The company was incorporated in 1981 and is headquartered in Waltham, Massachusetts.