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Upturn AI Summary - About
Repligen Corporation(RGEN)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Advisory Performance History (Simulated)
Upturn Advisory & Investor View for RGEN
11/05/2026: RGEN (2-star) is currently NOT-A-BUY. Pass it for now.
Repligen Corporation is a specialized life sciences company providing essential, high-quality components for biopharmaceutical manufacturing. It is recognized for its high-margin consumable products, such as chromatography resins and filtration membranes, which are often specified early in drug development. Its primary investment story centers on the secular growth of biologic drugs, including cell and gene therapies. However, the company faces risks from industry-wide inventory cycles, intense competition from diversified life science giants, and valuation sensitivity. While Repligen has a leading position in its niches, it is a volatile growth stock suited for investors comfortable with sector-specific cycles rather than those seeking dividends or low-risk stability.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Strong fit | Repligen serves the high-growth bioprocessing market which benefits from the secular increase in biologic drug development. |
| Momentum investor | Mixed fit | The stock often tracks industry-wide bioprocessing sentiment and requires a positive sector upturn signal to confirm momentum. |
| Value investor | Weak fit | The stock frequently trades at a premium valuation due to its high-quality growth characteristics and specialized niche status. |
| Dividend investor | Weak fit | Repligen does not pay a dividend and focuses on reinvesting cash for growth. |
| Low-risk investor | Weak fit | The stock exhibits high volatility characteristic of small-to-mid-cap growth stocks in the biotechnology tools sector. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock is susceptible to sharp swings based on industry inventory cycles and biopharma capital spending. |
| Valuation risk | Medium / high | Investors often pay a premium for growth, which can lead to rapid price corrections if growth expectations are not met. |
| Competition risk (Diversified Life Science Providers) | Medium | Larger companies like Thermo Fisher and Danaher can leverage their scale to pressure pricing or bundle offerings. |
| Business quality | Strong | Repligen has high margins and a strong, recurring revenue model tied to essential bioprocessing consumables. |
| Dividend income | Low / none | Investors should not expect income, as all capital is directed toward growth and operations. |
| Execution risk | Medium | Successful growth depends on integrating acquisitions and maintaining technical relevance in a fast-evolving market. |
Price Behavior

Strong Uptrend
The stock has maintained a strong upward price trend across the last three quarters.

Moderately Choppy
The stock has experienced noticeable price swings while retaining some directional structure.
Analysis of Past Performance
Type Stock | Historic Profit 0.22% | Avg. Invested days 41 | Today’s Advisory PASS |
Upturn Advisory Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals 
Financial Health Rating 
Growth Momentum Score 
Ownership 
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue) 
Economic Dimensions
Quantitative Style Profile 
Style Classification
Quality Focused
Key Highlights
Company Size Large-Cap Stock | Market Capitalization 11.39B USD | Price to earnings Ratio - | 1Y Target Price 203.45 |
Price to earnings Ratio - | 1Y Target Price 203.45 | ||
Volume (30-day avg) 1.4M shares | Beta 1.12 | 52 Weeks Range 100.99 - 198.87 | Updated Date 11/05/2026 |
52 Weeks Range 100.99 - 198.87 | Updated Date 11/05/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.21 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Bioprocessing Consumables | Resins, filters, and fluid management components used in drug production. | The company earns the majority of its revenue from parts that biopharma companies must buy repeatedly. |
| Process Analytics & Equipment | Sensors and chromatography columns for monitoring and purification. | This segment provides the technology to ensure the quality of high-value medicine production. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date 2026-10-27 | When Before Market | Estimate 0.46 | Actual 0.53 |
Profitability
Profit Margin -1.47% | Operating Margin (TTM) 6.19% |
Management Effectiveness
Return on Assets (TTM) 1.4% | Return on Equity (TTM) -0.57% |
Valuation
Trailing PE - | Forward PE 62.11 | Enterprise Value 10.81B | Price to Sales(TTM) 14.14 |
Enterprise Value 10.81B | Price to Sales(TTM) 14.14 | ||
Enterprise Value to Revenue 13.42 | Enterprise Value to EBITDA 84.88 | Shares Outstanding 63.92M | Shares Floating 60.96M |
Shares Outstanding 63.92M | Shares Floating 60.96M | ||
Percent Insiders 4.63 | Percent Institutions 105.24 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

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