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Repligen Corporation(RGEN)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL RECENCY
2-STAR RATING
Consider higher Upturn Star rating
BUY for 36 days
PROFIT SINCE LAST BUY
+20.22% ▲
LAST CLOSE
$190.65
09/24/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for RGEN

09/24/2026: RGEN (2-star) has a low Upturn Star Rating. Not recommended to BUY.

Repligen Corporation is a specialized life sciences tools company providing essential components for the manufacturing of biological drugs. The company has a leading position in niche bioprocessing segments such as chromatography and filtration, which historically support high-margin, recurring revenue streams. Its primary growth opportunity lies in the expanding demand for complex biological therapies and the adoption of modern, automated bioprocessing workflows. However, the company faces risks related to biopharma capital expenditure cycles, high valuation multiples, and competition from large, diversified life sciences firms. Repligen is best suited for growth-oriented investors and should be monitored for recovery trends in biopharma manufacturing.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitThe company operates in the high-growth bioprocessing sector with a track record of expanding its market share.
Momentum investorMixed fitMomentum depends on a sustained industry upturn in biopharma manufacturing demand.
Value investorWeak fitRepligen often trades at a high P/E multiple consistent with growth-oriented biotech tools firms.
Dividend investorWeak fitThe company does not currently pay a dividend and reinvests all cash flow into growth.
Low-risk investorWeak fitHigh valuation multiples and sensitivity to biopharma cycles lead to significant stock price volatility.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock is subject to significant swings based on biopharma sector sentiment.
Valuation riskMedium / highHigh growth expectations are priced into the stock, leaving little margin for error.
Competition risk (Diversified life sciences giants)MediumLarger companies with broader portfolios can bundle products and pressure pricing.
Business qualityStrongThe company possesses high-quality recurring revenue from consumables and a defensible niche.
Dividend incomeLow / noneInvestors should not expect income generation from this holding.
Execution riskMediumSuccessfully integrating future acquisitions is vital to maintaining growth.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Moderately Choppy
PRICE STABILITY

Moderately Choppy

The stock has experienced noticeable price swings while retaining some directional structure.

Analysis of Past Performance

Type Stock
Historic Profit 16.61%
Avg. Invested days 40
Today’s Advisory Consider higher Upturn Star rating
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 3.0
Stock Returns Performance Upturn Returns Performance icon 2.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/24/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
RGEN receives a 3-star rating, supported by solid company fundamentals, and solid analyst coverage. The rating is constrained by weak price momentum, and limited analyst upside.

Company Fundamentals

★★★★★
RGEN has solid overall fundamentals (4 stars), with moderate financial health, solid growth momentum, and strong ownership. In FY2025 versus FY2024, strong earnings growth (+291.6%) and solid cash generation (FCF margin 12.7%) are partially offset by soft profitability (net margin 6.6%).

Financial Health Rating

★★★★★
RGEN's financial health is supported by solid cash strength, including free-cash-flow generation (12.7% of revenue). Profitability is moderate (3 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is RGEN's strongest growth driver at +291.6% FY2025 versus FY2024 (strong, 5 stars). By comparison, revenue growth (+16.4%, solid) is also solid, while free-cash-flow growth (-34.1%, negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 120.0% and approximately 94.8% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 5.25% supports management-shareholder alignment.

Top 5 Institutional Investors

BlackRock Inc 10.62%
T. Rowe Price Associates, Inc. 8.64%
FMR Inc 5.12%
United Capital Financial Advisers Inc 4.92%
Vanguard Capital Management, LLC 4.25%

Unit Economics (Per $1K Revenue)

★★★★★
RGEN generates approximately $471 of gross profit, $81 of operating income, and $127 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: 21.62%

Quantitative Style Profile

★★★★★
RGEN has a large-cap, liquid profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

Large / Mega Cap StabilityShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Large-Cap Stock
Market Capitalization 10.76B USD
Price to earnings Ratio 250.86
1Y Target Price 189.48
Price to earnings Ratio 250.86
1Y Target Price 189.48
Volume (30-day avg) 998.7K shares
Beta 1.05
52 Weeks Range 100.99 - 192.49
Updated Date 09/25/2026
52 Weeks Range 100.99 - 192.49
Updated Date 09/25/2026
Dividends yield (FY) -
Basic EPS (TTM) 0.76

How Company Makes Money

Business areaWhat it includesRetail investor read
ConsumablesResins, filters, and membranes used repeatedly in manufacturing.The vast majority of revenue is recurring, which is excellent for long-term stability.
EquipmentChromatography systems and sensors.These are capital sales that lead to long-term demand for the company's consumables.
GeographyNorth America, Europe, and Asia-Pacific sales.Global exposure provides a hedge against regional biopharma slowdowns.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

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Valuation

Trailing PE 250.86
Forward PE 67.11
Enterprise Value 10.29B
Price to Sales(TTM) 13.7
Enterprise Value 10.29B
Price to Sales(TTM) 13.7
Enterprise Value to Revenue 11.72
Enterprise Value to EBITDA 53.61
Shares Outstanding 56.44M
Shares Floating 53.47M
Shares Outstanding 56.44M
Shares Floating 53.47M
Percent Insiders 5.25
Percent Institutions 120.04

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI Summary

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Repligen Corporation

Exchange NASDAQ
Headquarters Waltham, MA, United States
IPO Launch date 1990-03-26
President, CEO & Director Mr. Olivier Loeillot
Sector Healthcare
Industry Medical Instruments & Supplies
Full time employees 2000
Full time employees 2000

Repligen Corporation, a life sciences company, develops and commercializes bioprocessing technologies and systems in North America, Europe, the Asia Pacific, and internationally. The company's products include hollow fiber consumables, KRM chromatography system, resins for new modalities, PATsmart MAVERICK and PATsmart MAVEN for real-time monitoring and control of critical bioprocess parameters, PATsmart REBEL, an at-line cell culture media analyzer; and PATsmart ZipChip, a high-resolution sample separations device, PATsmart SoloVPE slope spectroscopy system, and SoloVPE PLUS System. It offers Protien A ligands that are the binding components of Protein A affinity chromatography resins; and cell culture growth factor products. The company also provides chromatography products, including OPUS pre-packed chromatography columns, which are used in the purification and quality control of biological drugs, as well as ELISA test kits. In addition, it offers filtration products, such as XCell ATF Cell Retention Systems that are filtration devices used in upstream perfusion and cell culture processing; TangenX flat sheet cassettes, which are used in downstream biologic drug concentration, buffer exchange, and formulation processes; KrosFlo tangential flow filtration and tangential flow depth filtration systems; and ProConnex TFDF flow paths. Further, it provides process analytics products, such as slope spectroscopy systems. The company offers its products under the OPUS, XCell, XCell ATF, TFDF, KrosFlo, SIUS, ProConnex, Spectra/Por, NGL-Impact, SoloVPE, FlowVPE, RPM, XO, Metenova MixOne, and AVIPure and FlowVPX brands. The company sells its products to life sciences, biopharmaceutical, and diagnostics companies; laboratory researchers; and contract manufacturing organizations. Repligen Corporation has a collaboration agreement with Navigo Proteins GmbH to develop multiple affinity ligands. The company was incorporated in 1981 and is headquartered in Waltham, Massachusetts.