Skye Bioscience, Inc. Common Stock logo

Skye Bioscience, Inc. Common Stock(SKYE)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$1.7
09/24/2026
(24-hour delay)

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*as per simulation (see disclosures)
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Upturn Advisory & Investor View for SKYE

09/24/2026: SKYE (1-star) is currently NOT-A-BUY. Pass it for now.

Skye Bioscience is a clinical-stage biotechnology company focused on developing therapies for metabolic and eye-related diseases, most notably through its CB1-targeting candidate, Nimacimab. Its core business strength lies in its strategic focus on the high-growth obesity market, offering a potential alternative to current weight-loss solutions. The company's primary growth opportunity centers on positive clinical trial results that could facilitate partnerships or acquisition. Investors face significant risks, including binary clinical outcomes, high cash burn, and intense competition from entrenched industry leaders. This stock is best suited for growth-oriented investors with a high risk tolerance who are closely monitoring clinical trial milestones and management's capital allocation strategy.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThis is a high-risk, high-reward play on clinical trial outcomes rather than a stable growth company.
Momentum investorStrong fit while signal remains positiveThe stock can experience significant moves based on news cycles or data readouts, attracting momentum interest.
Value investorWeak fitLack of earnings and product revenue makes traditional value metrics inapplicable.
Dividend investorWeak fitThe company does not pay a dividend and focuses entirely on capital reinvestment.
Low-risk investorWeak fitBiotechnology development carries inherent volatility and binary risk that is unsuitable for risk-averse investors.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical-stage stocks are prone to large price swings based on trial results and regulatory news.
Valuation riskHighValuations are speculative and depend heavily on future success that is not guaranteed.
Competition risk (metabolic drug market)HighIncumbent players have massive resources and entrenched market positions.
Business qualityMediumThe company relies on its ability to execute clinical programs effectively.
Dividend incomeLow / noneThere is no income generation for shareholders.
Execution riskHighFailure at any stage of the clinical pipeline could jeopardize the business viability.

Price Behavior

Strong Uptrend
PRICE PATH

Strong Uptrend

The stock has maintained a strong upward price trend across the last three quarters.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -27.22%
Avg. Invested days 22
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/24/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
SKYE receives a 2-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
SKYE has moderate overall fundamentals (3 stars), with moderate financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-110.5%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
SKYE's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
SKYE's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-110.5%, negative) and free-cash-flow growth (-60.5%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 43.7% and approximately 63.4% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 4.24% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

5AM Venture Management, LLC 27.33%
Versant Venture Management LLC 5.67%
Baker Bros Advisors LP 4.45%
Vanguard Capital Management, LLC 2.16%
Sphera Funds Management Ltd. 1.92%

Unit Economics (Per $1K Revenue)

★★★★★
SKYE generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

★★★★★
Effective Tax Rate: -0.01% (Tax Credit)

Quantitative Style Profile

★★★★★
SKYE has a liquid profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 7.97M USD
Price to earnings Ratio -
1Y Target Price 68
Price to earnings Ratio -
1Y Target Price 68
Volume (30-day avg) 794.5K shares
Beta 2.9
52 Weeks Range 0.26 - 4.99
Updated Date 09/24/2026
52 Weeks Range 0.26 - 4.99
Updated Date 09/24/2026
Dividends yield (FY) -
Basic EPS (TTM) -10.69

How Company Makes Money

Business areaWhat it includesRetail investor read
Drug DevelopmentClinical trial candidates including Nimacimab.The company does not currently generate product revenue and relies on potential future drug approvals.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value -2.31M
Price to Sales(TTM) 117.9
Enterprise Value -2.31M
Price to Sales(TTM) 117.9
Enterprise Value to Revenue 220.74
Enterprise Value to EBITDA -2.56
Shares Outstanding 4.43M
Shares Floating 2.81M
Shares Outstanding 4.43M
Shares Floating 2.81M
Percent Insiders 4.24
Percent Institutions 43.73

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Skye Bioscience, Inc. Common Stock

Exchange NASDAQ
Headquarters San Diego, CA, United States
IPO Launch date 2015-04-02
President, CEO & Director Mr. Punit S. Dhillon B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 2
Full time employees 2

Skye Bioscience, Inc., a clinical-stage biotechnology company, develops molecules that modulate G-protein-coupled receptors to treat obesity, overweight, and related metabolic diseases. The company's lead clinical asset is nimacimab, a peripherally-restricted negative allosteric modulating antibody targeting cannabinoid receptor 1 (CB1) administered as a subcutaneous injectable, which targets CB1 receptors in peripheral tissues including adipose, liver, and muscle tissues with limited central nervous system accumulation. Nimacimab addresses metabolic processes related to energy expenditure, fat mobilization, leptin sensitivity, appetite regulation, and satiety signaling. Skye Bioscience, Inc. was formerly known as Emerald Bioscience Inc. and changed its name to Skye Bioscience, Inc. in December 2020. Skye Bioscience, Inc. was incorporated in 2011 and is based in San Diego, California.