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Shattuck Labs Inc (STTK)

Upturn stock ratingUpturn stock rating
$0.86
Last Close (24-hour delay)
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
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Upturn Advisory Summary

08/14/2025: STTK (2-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Below Average Performance

These Stocks/ETFs, based on Upturn Advisory, often underperform the market, warranting careful consideration before investing.

Number of Analysts

rating

5 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $1.46

1 Year Target Price $1.46

Analysts Price Target For last 52 week
$1.46 Target price
52w Low $0.69
Current$0.86
52w High $3.95

Analysis of Past Performance

Type Stock
Historic Profit 74.7%
Avg. Invested days 22
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 1.0
Stock Returns Performance Upturn Returns Performance 4.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 08/14/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 47.90M USD
Price to earnings Ratio -
1Y Target Price 1.46
Price to earnings Ratio -
1Y Target Price 1.46
Volume (30-day avg) 5
Beta 1.64
52 Weeks Range 0.69 - 3.95
Updated Date 08/15/2025
52 Weeks Range 0.69 - 3.95
Updated Date 08/15/2025
Dividends yield (FY) -
Basic EPS (TTM) -1.39

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Earnings Date

Report Date 2025-08-14
When -
Estimate -0.245
Actual -0.24

Profitability

Profit Margin -
Operating Margin (TTM) -1621.58%

Management Effectiveness

Return on Assets (TTM) -41.77%
Return on Equity (TTM) -71.9%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -16489074
Price to Sales(TTM) 10.4
Enterprise Value -16489074
Price to Sales(TTM) 10.4
Enterprise Value to Revenue 18.32
Enterprise Value to EBITDA -3.62
Shares Outstanding 47903200
Shares Floating 24146965
Shares Outstanding 47903200
Shares Floating 24146965
Percent Insiders 14.36
Percent Institutions 57.84

ai summary icon Upturn AI SWOT

Shattuck Labs Inc

stock logo

Company Overview

overview logo History and Background

Shattuck Labs, Inc. is a clinical-stage biotechnology company pioneering the development of transformative medicines for the treatment of cancer and autoimmune disease. Founded in 2011, it focuses on developing Agonist Redirected Checkpoint (ARCu00ae) therapeutics.

business area logo Core Business Areas

  • ARCu00ae Platform Development: Developing and researching new molecules using their ARCu00ae platform.
  • Oncology: Developing therapies to treat different forms of cancer.
  • Immunology: Developing therapies targeting autoimmune and inflammatory disorders.

leadership logo Leadership and Structure

The leadership team includes Josie Cook, Chief Executive Officer and Gregg Beloff, Chief Financial Officer. The company has a board of directors that oversees operations.

Top Products and Market Share

overview logo Key Offerings

  • SL-172154 (SIRPu03b1-Fc-CD40L): A lead clinical program targeting advanced ovarian cancer and other solid tumors. Currently in Phase 1 clinical trials. Competitors include other immuno-oncology approaches and checkpoint inhibitors from companies like Merck (MRK) and Bristol Myers Squibb (BMY).
  • SL-279252 (PD-L1-Fc-OX40): Another clinical program being developed for cancer. This also is in Phase 1 clinical trials. Competitors include other immuno-oncology approaches and checkpoint inhibitors from companies like Roche (RHHBY) and AstraZeneca (AZN).

Market Dynamics

industry overview logo Industry Overview

The biotechnology industry is highly competitive and focused on developing new therapies for diseases with unmet medical needs. It involves significant research and development expenditure with uncertain outcomes and long development timelines.

Positioning

Shattuck Labs is positioned as a company developing novel immunotherapies using its ARCu00ae platform, competing with larger pharmaceutical and biotech companies.

Total Addressable Market (TAM)

The TAM for cancer and autoimmune disease therapies is substantial, estimated in the hundreds of billions of dollars. Shattuck Labs is focused on a niche within this market, targeting specific mechanisms of action with its ARCu00ae platform.

Upturn SWOT Analysis

Strengths

  • Novel ARCu00ae platform technology
  • Experienced leadership team
  • Proprietary technology
  • Focus on unmet medical needs

Weaknesses

  • Reliance on early-stage clinical programs
  • High cash burn rate
  • Dependence on external funding
  • Limited commercialization experience

Opportunities

  • Positive clinical trial results
  • Strategic partnerships with larger pharmaceutical companies
  • Expansion of the ARCu00ae platform to new targets
  • Acquisition by a larger pharmaceutical company

Threats

  • Clinical trial failures
  • Competition from established therapies
  • Regulatory hurdles
  • Economic downturn affecting funding

Competitors and Market Share

competitor logo Key Competitors

  • MRK
  • BMY
  • AZN
  • RHHBY

Competitive Landscape

Shattuck Labs faces significant competition from established pharmaceutical companies with greater resources. Its competitive advantage lies in its novel ARCu00ae platform, but it needs to demonstrate clinical efficacy and safety.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is defined by R&D to bring drugs to market.

Future Projections: Future growth depends on the successful clinical development and commercialization of its ARCu00ae therapeutics. Analyst estimates vary, but generally project revenue growth upon successful commercialization.

Recent Initiatives: Recent initiatives include advancing clinical trials for SL-172154 and SL-279252, and exploring new applications for the ARCu00ae platform.

Summary

Shattuck Labs is a high-risk, high-reward biotechnology company focused on novel immunotherapies. Its ARCu00ae platform offers potential advantages, but clinical success is uncertain. The company faces significant competition and requires substantial funding to continue operations. Success is dependent on clinical trials progressing to successful commercial outcomes.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Analyst Reports

Disclaimers:

This analysis is for informational purposes only and does not constitute financial advice. Investment decisions should be based on your own research and due diligence.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Shattuck Labs Inc

Exchange NASDAQ
Headquaters Austin, TX, United States
IPO Launch date 2020-10-09
Co-Founder, CEO & Director Dr. Taylor H. Schreiber M.D., Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 44
Full time employees 44

Shattuck Labs, Inc., a biotechnology company, develops antibodies for the treatment of inflammatory and immune-mediated diseases. The company's lead product candidate includes SL-325, a DR3 blocking monoclonal antibody, which activates immune responses through binding a single receptor, DR3; and SL-425. It also develops multiple preclinical DR3-based bispecific antibodies for the treatment of inflammatory bowel disease; and a series of bispecific antibodies targeting DR3 and other clinically validated targets. In addition, the company is involved in the advancement of its lead TRIM7 inhibitors through preclinical development as future internal pipeline candidates in oncology. Shattuck Labs, Inc. was incorporated in 2016 and is headquartered in Austin, Texas.