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Tscan Therapeutics Inc (TCRX)
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Upturn Advisory Summary
12/09/2024: TCRX (3-star) is currently NOT-A-BUY. Pass it for now.
Analysis of Past Performance
Type: Stock | Upturn Star Rating | Today’s Advisory: PASS |
Historic Profit: -25% | Upturn Advisory Performance 3 | Avg. Invested days: 32 |
Profits based on simulation | Stock Returns Performance 1 | Last Close 12/09/2024 |
Type: Stock | Today’s Advisory: PASS |
Historic Profit: -25% | Avg. Invested days: 32 |
Upturn Star Rating | Stock Returns Performance 1 |
Profits based on simulation Last Close 12/09/2024 | Upturn Advisory Performance 3 |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 239.63M USD |
Price to earnings Ratio - | 1Y Target Price 12.57 |
Dividends yield (FY) - | Basic EPS (TTM) -0.95 |
Volume (30-day avg) 253953 | Beta 0.78 |
52 Weeks Range 3.92 - 9.69 | Updated Date 12/9/2024 |
Company Size Small-Cap Stock | Market Capitalization 239.63M USD | Price to earnings Ratio - | 1Y Target Price 12.57 |
Dividends yield (FY) - | Basic EPS (TTM) -0.95 | Volume (30-day avg) 253953 | Beta 0.78 |
52 Weeks Range 3.92 - 9.69 | Updated Date 12/9/2024 |
Earnings Date
Report Date 2024-11-12 | When - |
Estimate -0.2918 | Actual -0.25 |
Report Date 2024-11-12 | When - | Estimate -0.2918 | Actual -0.25 |
Profitability
Profit Margin - | Operating Margin (TTM) -3109.82% |
Management Effectiveness
Return on Assets (TTM) -23.36% | Return on Equity (TTM) -55.92% |
Valuation
Trailing PE - | Forward PE - |
Enterprise Value 58869966 | Price to Sales(TTM) 25.6 |
Enterprise Value to Revenue 6.29 | Enterprise Value to EBITDA 0.39 |
Shares Outstanding 49094000 | Shares Floating 31132669 |
Percent Insiders 0.82 | Percent Institutions 86 |
Trailing PE - | Forward PE - | Enterprise Value 58869966 | Price to Sales(TTM) 25.6 |
Enterprise Value to Revenue 6.29 | Enterprise Value to EBITDA 0.39 | Shares Outstanding 49094000 | Shares Floating 31132669 |
Percent Insiders 0.82 | Percent Institutions 86 |
Analyst Ratings
Rating 4.5 | Target Price 10.75 | Buy 4 |
Strong Buy 4 | Hold - | Sell - |
Strong Sell - |
Rating 4.5 | Target Price 10.75 | Buy 4 | Strong Buy 4 |
Hold - | Sell - | Strong Sell - |
AI Summarization
Tscan Therapeutics Inc. (TCRN): A Comprehensive Overview
Company Profile:
History and Background: Founded in 2007, Tscan Therapeutics Inc. is a clinical-stage biopharmaceutical company engaged in the development of innovative T cell receptor (TCR) therapies for the treatment of cancer. Initially focusing on T cell activation therapies, the company shifted its focus to TCR-T cell therapies in 2015. Tscan boasts a proprietary technology platform leveraging its deep understanding of TCR biology and engineering to develop highly selective and effective TCR-T cell therapies.
Core Business Areas: Tscan primarily focuses on developing and commercializing TCR-T cell therapies for the treatment of hematological malignancies and solid tumors. Their pipeline comprises several innovative candidates at different development stages, targeting various types of cancer, including acute myeloid leukemia (AML), T-cell lymphoma, and multiple myeloma.
Leadership Team and Corporate Structure:
- President & CEO: Terrence G. Piwon, Ph.D.
- Executive Vice President & COO: Stephen R. Kim, Ph.D.
- Executive Vice President & CMO: Christopher M. O'Mara, M.D.
- Executive Vice President, Head of Research & Development: Michael B. Datto, Ph.D.
The company has a Board of Directors with a strong scientific and business background, guiding the overall strategic direction of the company.
Top Products and Market Share:
Tscan's Top Product: Currently, Tscan has no approved product in the market. However, their lead product candidate, TC-210, a TCR-T cell therapy targeting T-cell lymphoma, is undergoing a Phase 1 clinical trial. The company expects to initiate a Phase 2 clinical trial for TC-210 in 2024.
Market Share: As Tscan does not yet have any marketed products, the company currently holds no market share in the TCR-T cell therapy market. However, the global TCR-T cell therapy market is rapidly growing, estimated to reach a value of $4.3 billion by 2026. With their promising pipeline and strong scientific expertise, Tscan has the potential to capture a significant share of this lucrative market.
Total Addressable Market: The current global market for CAR-T cell therapy stands at approximately $2 billion, with an expected growth to reach $6.4 billion by 2027. As TCR-T cell therapy is an emerging field with immense potential, this market is expected to grow even more significantly, opening up massive opportunities for Tscan to tap into.
Financial Performance:
Recent Financial Statements: Tscan is a pre-revenue company, meaning they are yet to generate significant revenue from product sales. Therefore, their recent financial statements primarily reflect research and development expenses, administrative costs, and other operating expenses.
Year-over-Year Performance: Tscan's research and development expenses have been steadily increasing over the past years, reflecting the company's focus on advancing its pipeline. However, with no market-approved products, they continue to incur net losses.
Cash Flow and Balance Sheet: Tscan's cash flow primarily consists of net proceeds from offerings of their common stock and grants received. As of December 31, 2022, the company had an estimated cash and cash equivalents balance of $49.7 million, providing sufficient runway for ongoing pipeline development.
Dividends and Shareholder Returns: Due to their developmental stage, Tscan has not yet declared or paid any dividends to shareholders. The company also does not have a current share repurchase program in place. Therefore, shareholder returns are primarily driven by the stock price appreciation.
Growth Trajectory: Tscan's growth potential is heavily reliant on the successful development and commercialization of their pipeline, particularly TC-210. The company's financial performance and future valuation will be directly linked to the clinical trial outcomes and subsequent market reception of their therapies.
Market Dynamics:
Industry Overview: The TCR-T cell therapy market is in its early stages of development, witnessing rapid growth driven by technological advancements and promising clinical data. This market is characterized by intense competition, as several other companies are vying for market leadership.
Tscan's Positioning: Tscan holds a differentiated position within the industry, leveraging its proprietary TCR engineering platform to develop highly selective and potent TCR-T cell therapies. They focus on developing therapies for high-unmet medical needs, targeting cancers with limited treatment options.
Competitors:
- TCR2 Therapeutics (TCRR)
- Adaptimmune Therapeutics (ADAP)
- Gilead Sciences (GILD)
- Juno Therapeutics (JUNO)
These companies are developing similar TCR-T cell therapies for various types of cancer, posing significant competition to Tscan in the market.
Recent Acquisitions:
Ganymed Pharmaceuticals Acquisition (2021): Tscan acquired Ganymed Pharmaceuticals to secure innovative pipeline assets and enhance their TCR-T cell therapy portfolio. This acquisition allowed Tscan to expand its focus into solid tumor indications, particularly targeting cancers with high unmet medical needs.
AI-Based Fundamental Rating:
Based on an AI-based fundamental analysis, Tscan Therapeutics Inc. receives an overall rating of 6 out of 10. The rating considers various factors, including their strong scientific and technical expertise, promising pipeline, and potentially robust market opportunities. However, the absence of marketed products, risks associated with clinical trial outcomes, and intense competition in the industry are reflected in the score.
Justification:
This moderate rating acknowledges Tscan's significant potential but also recognizes the risks and challenges associated with their stage of development. The company's success hinges on successful clinical trials, regulatory approvals, and achieving commercial viability for their TCR-T cell therapies.
Sources and Disclaimers:
Sources:
- Tscan Therapeutics Inc. Investor Relations website
- SEC filings
- Market research reports
- Industry news articles
Disclaimer:
This information is provided for educational purposes only and should not be considered investment advice. It is crucial to conduct thorough research and seek professional financial advice before making any investment decisions.
Conclusion:
Tscan Therapeutics Inc. presents a high-risk, high-reward investment opportunity. The company holds significant potential with its innovative approach to TCR-T cell therapies. Their success hinges on their ability to navigate clinical development challenges, achieve commercialization, and gain market traction within the competitive landscape. Investors should carefully assess the risks and potential rewards before investing in Tscan.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Tscan Therapeutics Inc
Exchange | NASDAQ | Headquaters | Waltham, MA, United States |
IPO Launch date | 2021-07-16 | CEO & Director | Dr. Gavin MacBeath Ph.D. |
Sector | Healthcare | Website | https://www.tscan.com |
Industry | Biotechnology | Full time employees | 188 |
Headquaters | Waltham, MA, United States | ||
CEO & Director | Dr. Gavin MacBeath Ph.D. | ||
Website | https://www.tscan.com | ||
Website | https://www.tscan.com | ||
Full time employees | 188 |
TScan Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops T cell receptor-engineered T cell (TCR-T) therapies for the treatment of patients with cancer in the United States. The company's lead product candidates include TSC-100 and TSC-101 that is in Phase I clinical trial for the treatment of patients with hematologic malignancies to eliminate residual disease and prevent relapse after allogeneic hematopoietic cell transplantation. It also develops TSC-200, TSC-201, TSC-203, and TSC-204, which are in Phase 1 clinical trial, for the treatment of solid tumors; and TSC-202 to treat solid tumors. In addition, the company develops vaccines for infectious diseases, such as SARS-CoV-2. It has collaborations with Novartis Institutes for BioMedical Research, Inc. To discover and develop novel TCR-T therapies; and Amgen Inc. to identify antigens recognized by T cells in patients with Crohn's disease using TargetScan, a proprietary target discovery platform. TScan Therapeutics, Inc. was incorporated in 2018 and is headquartered in Waltham, Massachusetts.
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