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TVTX
Upturn stock ratingUpturn stock rating

Travere Therapeutics Inc (TVTX)

Upturn stock ratingUpturn stock rating
$15.11
Delayed price
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

04/21/2025: TVTX (3-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

ratingratingratingratingrating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Analysis of Past Performance

Type Stock
Historic Profit 18.81%
Avg. Invested days 32
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 2.0
Stock Returns Performance Upturn Returns Performance 2.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 04/21/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.41B USD
Price to earnings Ratio -
1Y Target Price 33.67
Price to earnings Ratio -
1Y Target Price 33.67
Volume (30-day avg) 1789274
Beta 0.84
52 Weeks Range 5.12 - 25.29
Updated Date 04/23/2025
52 Weeks Range 5.12 - 25.29
Updated Date 04/23/2025
Dividends yield (FY) -
Basic EPS (TTM) -4.07

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -137.9%
Operating Margin (TTM) -79.34%

Management Effectiveness

Return on Assets (TTM) -23.15%
Return on Equity (TTM) -246.75%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 1440577262
Price to Sales(TTM) 6.05
Enterprise Value 1440577262
Price to Sales(TTM) 6.05
Enterprise Value to Revenue 6.18
Enterprise Value to EBITDA -5.67
Shares Outstanding 88771696
Shares Floating 75629404
Shares Outstanding 88771696
Shares Floating 75629404
Percent Insiders 0.7
Percent Institutions 109.22

Analyst Ratings

Rating 4.56
Target Price 33.67
Buy 3
Strong Buy 11
Buy 3
Strong Buy 11
Hold 2
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

Travere Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

Travere Therapeutics Inc. was founded in 2011. It's a biopharmaceutical company focused on developing and commercializing therapies for rare diseases. Originally known as CymaBay Therapeutics, it shifted its focus and rebranded to Travere Therapeutics.

business area logo Core Business Areas

  • Rare Kidney Diseases: Focuses on developing and commercializing therapies for rare kidney diseases like FSGS and IgAN.
  • Rare Liver Diseases: Historically involved in developing therapies for rare liver diseases; currently focused on kidney diseases.

leadership logo Leadership and Structure

Eric Dube is the CEO. The company has a typical biopharmaceutical organizational structure with departments for R&D, commercial operations, and corporate functions.

Top Products and Market Share

overview logo Key Offerings

  • Filspari (sparsentan): A dual endothelin angiotensin receptor antagonist indicated to reduce proteinuria in adults with primary IgAN at risk of rapid disease progression. Competitors include generic blood pressure medications and other therapies targeting IgAN progression. Market share data is still developing as Filspari is a relatively new therapy.
  • Cholbam (cholic acid): Indicated for bile acid synthesis disorders and Zellweger spectrum disorders. Revenue generated from Cholbam for FY2023 was $42.3 million. Competitors include other bile acid therapies and supportive care treatments.

Market Dynamics

industry overview logo Industry Overview

The rare disease therapeutics market is a growing segment of the pharmaceutical industry. It is driven by unmet medical needs and regulatory incentives. The sector is competitive, with companies developing novel therapies and seeking orphan drug designations.

Positioning

Travere Therapeutics is positioned as a company focused on rare kidney diseases, particularly IgAN, with Filspari being its key growth driver. Its competitive advantage lies in addressing a specific unmet need with a novel mechanism of action.

Total Addressable Market (TAM)

The IgAN market is estimated to be multi-billion dollars annually. Travere Therapeutics is positioned to capture a significant share of this market with Filspari, provided it obtains full FDA approval and secures favorable reimbursement.

Upturn SWOT Analysis

Strengths

  • Novel therapy for IgAN (Filspari)
  • Experienced management team
  • Focus on rare diseases
  • Orphan drug designation benefits

Weaknesses

  • Reliance on a limited product portfolio
  • Commercialization risks associated with new product launches
  • Potential for regulatory setbacks
  • Dependence on successful clinical trials

Opportunities

  • Expansion of Filspari's indications
  • Development of new therapies for other rare diseases
  • Strategic partnerships and acquisitions
  • Geographic expansion

Threats

  • Competition from other IgAN therapies
  • Pricing pressures and reimbursement challenges
  • Clinical trial failures
  • Patent expirations

Competitors and Market Share

competitor logo Key Competitors

  • GSK (GSK)
  • Novartis (NVS)
  • Calliditas Therapeutics (CALT)

Competitive Landscape

Travere Therapeutics competes with established pharmaceutical companies and other biotechs in the rare disease space. Its competitive advantage relies on the novelty and efficacy of its therapies.

Major Acquisitions

Growth Trajectory and Initiatives

Historical Growth: Growth has been driven by the launch and ramp-up of Filspari sales.

Future Projections: Analysts project revenue growth for the coming years, driven by increased Filspari adoption and potential label expansion. Profitability is expected to improve as revenue increases.

Recent Initiatives: Focus on the global launch of Filspari and the pursuit of full FDA approval. Development of other pipeline candidates.

Summary

Travere Therapeutics is a biopharmaceutical company focused on rare kidney diseases. The launch of Filspari for IgAN is a key growth driver, but they face competition and regulatory risks. The company is not yet profitable, but revenue is projected to grow. Success is dependent on Filspari's continued success and pipeline development, and they must be watchful of competitors and regulatory setbacks.

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Sources and Disclaimers

Data Sources:

  • Company SEC Filings (10-K, 10-Q)
  • Company Investor Relations
  • Analyst Reports
  • Company Website

Disclaimers:

This analysis is based on publicly available information and is not financial advice. Market conditions and company performance may change. Consult a financial professional before making investment decisions.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Travere Therapeutics Inc

Exchange NASDAQ
Headquaters San Diego, CA, United States
IPO Launch date 2012-11-08
President, CEO & Director Dr. Eric M. Dube Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 385
Full time employees 385

Travere Therapeutics, Inc., a biopharmaceutical company, identifies, develops, and delivers therapies to people living with rare kidney and metabolic diseases in the United States. The company's products include FILSPARI (sparsentan), a once-daily, oral medication designed to target two critical pathways in the disease progression of IgA Nephropathy (endothelin 1 and angiotensin-II); and Thiola and Thiola EC (tiopronin tablets) for the treatment of cystinuria, a rare genetic cystine transport disorder that causes high cystine levels in the urine and the formation of recurring kidney stones. Its clinical-stage programs consist of Sparsentan, a novel investigational product candidate, which has been granted Orphan Drug Designation for the treatment of focal segmental glomerulosclerosis in the U.S. and Europe; and Pegtibatinase (TVT-058), a novel investigational human enzyme replacement candidate being evaluated for the treatment of classical homocystinuria. It has a collaboration agreement with PharmaKrysto Limited for the pre-clinical activities associated with the cystinuria program. The company was formerly known as Retrophin, Inc. and changed its name to Travere Therapeutics, Inc. in November 2020. Travere Therapeutics, Inc. was incorporated in 2008 and is headquartered in San Diego, California.

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