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ZBIO logo ZBIO
Upturn stock rating
ZBIO logo

Zenas BioPharma, Inc. Common Stock (ZBIO)

Upturn stock rating
$26.99
Last Close (24-hour delay)
Profit since last BUY60.46%
upturn advisory
Consider higher Upturn Star rating
BUY since 43 days
  • BUY Advisory
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  • SELL Advisory (Loss)​
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Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
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  • WEEK

Upturn Advisory Summary

10/15/2025: ZBIO (1-star) has a low Upturn Star Rating. Not recommended to BUY.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

7 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $34.29

1 Year Target Price $34.29

Analysts Price Target For last 52 week
$34.29 Target price
52w Low $5.83
Current$26.99
52w High $29.73

Analysis of Past Performance

Type Stock
Historic Profit 2.1%
Avg. Invested days 29
Today’s Advisory Consider higher Upturn Star rating
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 1.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/15/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.14B USD
Price to earnings Ratio -
1Y Target Price 34.29
Price to earnings Ratio -
1Y Target Price 34.29
Volume (30-day avg) 7
Beta -
52 Weeks Range 5.83 - 29.73
Updated Date 10/17/2025
52 Weeks Range 5.83 - 29.73
Updated Date 10/17/2025
Dividends yield (FY) -
Basic EPS (TTM) -12.29

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -1260.67%

Management Effectiveness

Return on Assets (TTM) -47.94%
Return on Equity (TTM) -88.4%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 609940057
Price to Sales(TTM) 76.04
Enterprise Value 609940057
Price to Sales(TTM) 76.04
Enterprise Value to Revenue 40.66
Enterprise Value to EBITDA -
Shares Outstanding 47110313
Shares Floating 13161578
Shares Outstanding 47110313
Shares Floating 13161578
Percent Insiders 29.87
Percent Institutions 71.2

ai summary icon Upturn AI SWOT

Zenas BioPharma, Inc. Common Stock

stock logo

Company Overview

overview logo History and Background

Zenas BioPharma is a global biopharmaceutical company committed to becoming a leader in the development and commercialization of meaningfully differentiated therapeutics for patients in need. Founded to address unmet medical needs, the company focuses on autoimmune diseases.

business area logo Core Business Areas

  • Immunology: Focuses on developing therapies for autoimmune diseases.

leadership logo Leadership and Structure

The leadership team consists of experienced professionals in the biopharmaceutical industry. Specifics on the team structure are typically available on the company's investor relations website and in SEC filings.

Top Products and Market Share

overview logo Key Offerings

  • Obexelimab: An investigational XmAbu00ae-based bispecific antibody targeting CD19 and Fcu03b3RIIb. Currently in clinical development for autoimmune diseases. Market share is currently 0 as the product is not yet approved. Competitors include established therapies for autoimmune diseases from companies like Roche (Rituxan), Johnson & Johnson (Stelara), and AbbVie (Humira).

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is characterized by high research and development costs, stringent regulatory requirements, and intense competition. Growth is driven by increasing prevalence of diseases, technological advancements, and aging populations.

Positioning

Zenas BioPharma aims to differentiate itself through novel therapeutic approaches, particularly bispecific antibodies. Their competitive advantage relies on the potential efficacy and safety profiles of their pipeline assets.

Total Addressable Market (TAM)

The autoimmune disease market is substantial, projected to reach hundreds of billions of dollars. Zenas aims to capture a portion of this TAM with Obexelimab and other pipeline assets, positioning itself to address underserved patient populations.

Upturn SWOT Analysis

Strengths

  • Novel therapeutic approach (bispecific antibodies)
  • Experienced management team
  • Focus on unmet medical needs in autoimmune diseases
  • Potential for differentiated efficacy and safety

Weaknesses

  • Dependence on pipeline progress
  • High R&D costs
  • Lack of currently marketed products
  • Susceptible to clinical trial failures

Opportunities

  • Partnerships with larger pharmaceutical companies
  • Expansion of pipeline through acquisitions or licensing
  • Positive clinical trial results
  • Approval and commercialization of Obexelimab

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from established therapies
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • RHHBY
  • JNJ
  • ABBV

Competitive Landscape

Zenas BioPharma competes with established pharmaceutical companies and other biotechnology firms developing therapies for autoimmune diseases. Their advantage lies in their bispecific antibody technology and focus on specific unmet needs.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is primarily measured by progress in clinical development and fundraising success.

Future Projections: Future growth depends on the successful development and commercialization of Obexelimab and other pipeline assets. Analyst estimates would be needed for specific revenue projections.

Recent Initiatives: Recent initiatives include advancing Obexelimab through clinical trials and exploring new therapeutic targets.

Summary

Zenas BioPharma is a clinical-stage biopharmaceutical company focused on developing treatments for autoimmune diseases using bispecific antibody technology. Their success hinges on the positive outcome of their clinical trials, specifically for Obexelimab. They face competition from established players in the pharmaceutical industry and must navigate regulatory hurdles. Their current financial health depends on continued fundraising and efficient use of capital. Their focus on unmet medical needs and innovative technology provide potential for future growth if clinical trials are positive.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company Website
  • SEC Filings
  • Industry Reports
  • Analyst Reports

Disclaimers:

This analysis is based on publicly available information and is for informational purposes only. It is not investment advice. Investment decisions should be made based on individual circumstances and consultation with a qualified financial advisor. Market share estimates are approximations.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Zenas BioPharma, Inc. Common Stock

Exchange NASDAQ
Headquaters Waltham, MA, United States
IPO Launch date 2024-09-13
CEO & Chairman of the Board Mr. Leon Oliver Moulder Jr., M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 130
Full time employees 130

Zenas BioPharma, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of transformative immunology-based therapies. Its lead product candidate is obexelimab, a bifunctional monoclonal antibody designed to bind CD19 and Fc"RIIb for the treatment of various I&I diseases and various indications, including immunoglobulin G4-related disease, multiple sclerosis, and systemic lupus erythematosus. The company also develops ZB002, an anti-TNFa monoclonal antibody; ZB004, a cytotoxic T-lymphocyte-associated antigen 4-immunoglobulin fusion; and ZB001, an anti-IGF-1R monoclonal antibody. The company was formerly known as Zenas BioPharma (Cayman) Limited and changed its name to Zenas BioPharma, Inc. in August 2023. The company was incorporated in 2019 and is headquartered in Waltham, Massachusetts.