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Zura Bio Limited Class A Ordinary Shares (ZURA)

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Upturn Advisory Summary
12/08/2025: ZURA (1-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $15.6
1 Year Target Price $15.6
| 5 | Strong Buy |
| 1 | Buy |
| 1 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -32.89% | Avg. Invested days 33 | Today’s Advisory WEAK BUY |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 243.19M USD | Price to earnings Ratio - | 1Y Target Price 15.6 |
Price to earnings Ratio - | 1Y Target Price 15.6 | ||
Volume (30-day avg) 7 | Beta 0.24 | 52 Weeks Range 0.97 - 4.68 | Updated Date 12/7/2025 |
52 Weeks Range 0.97 - 4.68 | Updated Date 12/7/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.65 |
Earnings Date
Report Date 2025-11-13 | When - | Estimate -0.31 | Actual -0.17 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -27.24% | Return on Equity (TTM) -45.01% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 104170171 | Price to Sales(TTM) - |
Enterprise Value 104170171 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -2.34 | Shares Outstanding 65023308 | Shares Floating 33377764 |
Shares Outstanding 65023308 | Shares Floating 33377764 | ||
Percent Insiders 27.75 | Percent Institutions 60.54 |
Upturn AI SWOT
Zura Bio Limited Class A Ordinary Shares

Company Overview
History and Background
Zura Bio Limited, trading as Class A Ordinary Shares, is a clinical-stage biopharmaceutical company focused on developing and commercializing novel therapies for immunology and oncology. The company was founded with the aim of addressing significant unmet medical needs in these complex disease areas. Significant milestones would include clinical trial initiations, regulatory interactions, and potential future financing rounds.
Core Business Areas
- Immunology: Development of therapeutics targeting inflammatory and autoimmune diseases, focusing on underlying mechanisms of immune dysregulation.
- Oncology: Research and development of innovative cancer treatments, potentially including immunotherapies or targeted therapies.
Leadership and Structure
Details on Zura Bio Limited's specific leadership team and organizational structure are typically found in their SEC filings (e.g., S-1, 10-K) and investor relations materials. This would include information on the Board of Directors, executive officers, and departmental organization.
Top Products and Market Share
Key Offerings
- Description: A novel therapeutic candidate in early-stage clinical development for an autoimmune indication. Market share data is not yet available as it is in development. Competitors would be companies developing therapies for the same autoimmune disease, such as AbbVie (Humira), Johnson & Johnson (Stelara), and Pfizer (Xeljanz).
- Market Share Data:
- Product Name: Zura Bio Pipeline Asset 1
- Description: A preclinical asset with potential application in oncology. Market share is not applicable at this stage. Competitors are broad and depend on the specific cancer type and therapeutic modality.
- Market Share Data:
- Product Name: Zura Bio Pipeline Asset 2
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly in immunology and oncology, is characterized by rapid scientific advancement, high R&D costs, intense competition, and significant regulatory hurdles. There is a strong demand for innovative treatments for chronic diseases and cancers with limited therapeutic options. The market is driven by unmet medical needs and the potential for blockbuster drug development.
Positioning
Zura Bio Limited is positioned as an emerging player in the biopharmaceutical space, aiming to leverage cutting-edge science to develop differentiated therapies. Its competitive advantage lies in its focus on novel mechanisms and potentially first-in-class or best-in-class drug candidates. However, as a clinical-stage company, it faces the inherent risks of drug development and competition from established pharmaceutical giants and other biotechs.
Total Addressable Market (TAM)
The TAM for Zura Bio Limited's target indications in immunology and oncology is substantial, potentially in the tens to hundreds of billions of dollars globally, depending on the specific diseases and stages of development. Zura Bio Limited is positioned to capture a niche within this TAM with its specialized pipeline.
Upturn SWOT Analysis
Strengths
- Focus on innovative, science-driven therapeutic candidates.
- Potential for first-in-class or best-in-class therapies.
- Experienced management and scientific team (assumed, requires verification).
Weaknesses
- Clinical-stage company with significant development and regulatory risks.
- Limited historical financial data and revenue generation.
- Dependence on successful clinical trial outcomes.
- High capital requirements for R&D.
Opportunities
- Addressing significant unmet medical needs in immunology and oncology.
- Potential for strategic partnerships and collaborations with larger pharmaceutical companies.
- Advancements in genetic sequencing and understanding of disease pathways.
- Emerging markets for biopharmaceuticals.
Threats
- Failure of clinical trials.
- Intense competition from established pharmaceutical companies and other biotechs.
- Regulatory hurdles and delays in drug approvals.
- Patent expirations and generic competition for existing treatments.
- Changes in healthcare policy and reimbursement.
Competitors and Market Share
Key Competitors
- AbbVie Inc. (ABBV)
- Johnson & Johnson (JNJ)
- Pfizer Inc. (PFE)
- Bristol Myers Squibb Company (BMY)
Competitive Landscape
Zura Bio Limited faces immense competition from large, established pharmaceutical companies with extensive portfolios, significant R&D budgets, and established sales forces. Its advantage lies in focusing on novel, potentially disruptive technologies or therapeutic pathways that larger companies may overlook or find too risky. However, it lacks the scale, resources, and market access of its major competitors.
Growth Trajectory and Initiatives
Historical Growth: Growth for Zura Bio Limited is measured by pipeline progression, such as the initiation and successful completion of clinical trial phases, and securing necessary funding. It is not driven by traditional revenue growth at this stage.
Future Projections: Future growth projections are highly speculative and depend entirely on the successful development and regulatory approval of its pipeline candidates. Analyst estimates, if available, would focus on potential peak sales of future drugs.
Recent Initiatives: Recent initiatives would typically involve advancing drug candidates into new clinical trial phases, securing strategic partnerships, or raising capital for further research and development.
Summary
Zura Bio Limited is a clinical-stage biopharmaceutical company with promising pipeline assets in immunology and oncology. Its strength lies in its scientific innovation and focus on unmet medical needs. However, it faces significant risks associated with drug development, intense competition, and substantial capital requirements. The company's future success hinges on successful clinical trials and regulatory approvals, necessitating careful monitoring of its pipeline progress and funding strategies.
Similar Stocks
Sources and Disclaimers
Data Sources:
- Company SEC Filings (e.g., S-1, 10-K, 10-Q)
- Financial News Outlets
- Industry Research Reports
- Biopharmaceutical Market Data Providers
Disclaimers:
This analysis is based on publicly available information and is for informational purposes only. It does not constitute investment advice. Investing in clinical-stage biopharmaceutical companies carries significant risk, and investors should conduct their own due diligence and consult with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Zura Bio Limited Class A Ordinary Shares
Exchange NASDAQ | Headquaters Henderson, NV, United States | ||
IPO Launch date 2021-09-03 | COO, Chief Legal Officer, Interim CEO & Corporate Secretary Ms. Kimberly Ann Davis J.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 30 | Website https://zurabio.com |
Full time employees 30 | Website https://zurabio.com | ||
Zura Bio Limited, a clinical-stage biotechnology company, develops medicines for immune and inflammatory disorders in the United States. The company develops Tibulizumab, an immunoglobulin G-single-chain variable fragment bispecific dual-antagonist antibody engineered by the fusion of ixekizumab and tabalumab that neutralizes interleukin (IL)-17A and B-cell activating factor, which is in Phase 2 clinical trial development. It is also developing Torudokimab (ZB-880), a monoclonal antibody that neutralizes IL-33 to prevent ST2-dependent and ST2-independent inflammation, which has completed Phase 1/2 clinical studies; and Crebankitug (ZB-168), a monoclonal antibody that binds and neutralizes the IL-7 receptor alpha chain that impact on diseases driven by IL-7 and thymic stromal lymphopoietin immune pathways, which has completed Phase 1/1b clinical studies. Zura Bio Limited was founded in 2022 and is headquartered in Henderson, Nevada.

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