Abeona Therapeutics Inc logo

Abeona Therapeutics Inc(ABEO)

upturn advisory logo
EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$4.17
11/06/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for ABEO

11/06/2026: ABEO (1-star) is currently NOT-A-BUY. Pass it for now.

Abeona Therapeutics is a clinical-stage biopharmaceutical company that recently achieved a significant milestone with the FDA approval of its lead gene therapy, pz-cel, for a rare skin condition. Its primary strength lies in its specialized gene therapy platform and its transition to a commercial-stage developer. The investment story centers on the potential market penetration and uptake of its newly approved therapy, which addresses a high-unmet-need condition. However, the company faces substantial execution, commercialization, and capital-related risks typical of small-cap biotech. This stock is best suited for investors with a high risk tolerance who are interested in the evolving rare disease therapy landscape and should closely monitor future commercial rollout updates.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers growth potential through its approved therapy but carries high operational risk.
Momentum investorWeak fitMomentum investment is conditional on sustained positive price trends which have been inconsistent.
Value investorWeak fitAbeona is a loss-making biotech firm and does not fit traditional value investment criteria.
Dividend investorWeak fitThe company does not pay dividends and focuses entirely on reinvesting capital into drug development.
Low-risk investorWeak fitThe high volatility and clinical-stage nature of the company are unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighBiotech stocks often experience extreme price swings based on clinical updates and funding announcements.
Valuation riskHighValuations in early commercial biotech are highly speculative and depend on future drug adoption curves.
Competition risk (rare disease gene therapies)HighThe sector is crowded with well-funded competitors developing alternative treatment modalities.
Business qualityMediumWhile the company has achieved regulatory success, it lacks a diverse, established commercial product portfolio.
Dividend incomeLow / noneInvestors should not expect income from this investment.
Execution riskHighSuccessfully manufacturing and launching a cell therapy at scale is complex and subject to significant operational hurdles.

Price Behavior

Rolling Over
PRICE PATH

Rolling Over

The price momentum is slowing down and beginning to turn downward.

Choppy
PRICE STABILITY

Choppy

The stock has experienced frequent reversals and pronounced short-term price swings.

Analysis of Past Performance

Type Stock
Historic Profit -45.72%
Avg. Invested days 30
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/06/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ABEO receives a 3-star rating, supported by solid company fundamentals, and solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
ABEO has solid overall fundamentals (4 stars), with moderate financial health, solid growth momentum, and strong ownership. In FY2025 versus FY2024, strong earnings growth (+211.7%) and strong profitability (net margin 1223.1%) are partially offset by weak cash generation (FCF margin -1448.5%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
ABEO's financial health is supported by solid profitability, including gross margin of 73.7% and operating margin of -1536.9%. Operating efficiency is soft (2 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is ABEO's strongest growth driver at +211.7% FY2025 versus FY2024 (strong, 5 stars). By comparison, while revenue growth (+0.0%, slightly negative) and free-cash-flow growth (-44.2%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 75.7% and approximately 63.3% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 12.29% supports management-shareholder alignment.

Top 5 Institutional Investors

Nantahala Capital Management, LLC 17.96%
BlackRock Inc 5.86%
Cable Car Capital LLC 5.26%
AIGH Capital Management, LLC 5.22%
Vanguard Capital Management, LLC 3.87%

Unit Economics (Per $1K Revenue)

★★★★★
ABEO generates approximately $737 of gross profit, $-15,369 of operating income, and $-14,485 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Operating losses and cash burn explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.14%

Quantitative Style Profile

★★★★★
ABEO has a liquid profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

Value-OrientedHigh VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 238.46M USD
Price to earnings Ratio -
1Y Target Price 18.88
Price to earnings Ratio -
1Y Target Price 18.88
Volume (30-day avg) 1.1M shares
Beta 1.48
52 Weeks Range 3.91 - 7.65
Updated Date 11/08/2026
52 Weeks Range 3.91 - 7.65
Updated Date 11/08/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.18

How Company Makes Money

Business areaWhat it includesRetail investor read
Cell and Gene TherapyRevenue derived from the commercialization of pz-cel for the treatment of RDEB.The company generates money by selling its recently approved gene therapy treatment to patients with a specific rare skin disease.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Valuation

Trailing PE -
Forward PE 18.66
Enterprise Value 111.50M
Price to Sales(TTM) 9.34
Enterprise Value 111.50M
Price to Sales(TTM) 9.34
Enterprise Value to Revenue 4.37
Enterprise Value to EBITDA 3.82
Shares Outstanding 57.18M
Shares Floating 36.18M
Shares Outstanding 57.18M
Shares Floating 36.18M
Percent Insiders 12.29
Percent Institutions 75.66

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

Form CRS provides a relationship summary of our automated advisory services, flat subscription fees, and conflicts of interest. Form ADV Part 2A brochure contains complete details on services, billing, and disclosures. If any summary differs from our current regulatory filings, the filed Form ADV controls.