Arvinas Inc logo

Arvinas Inc(ARVN)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$7.51
09/28/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Upturn Advisory & Investor View for ARVN

09/28/2026: ARVN (1-star) is currently NOT-A-BUY. Pass it for now.

Arvinas Inc is a clinical-stage biotechnology company that has established a leading position in the emerging field of targeted protein degradation through its proprietary PROTAC platform. The company's main strength lies in its innovative drug discovery engine and key strategic partnerships with major pharmaceutical entities like Pfizer. The primary investment story centers on the potential for its lead drug candidates to transform treatments for complex cancers and neurodegenerative diseases. However, investors must consider the significant risks associated with the high failure rate of clinical trials and the company's current lack of recurring revenue. Arvinas may best suit growth-oriented investors who are willing to accept high volatility in exchange for potential breakthroughs.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorStrong fitArvinas offers high-growth potential linked to its disruptive protein degradation platform.
Momentum investorMixed fitStrong fit while clinical trial signals and partnership news remain positive for stock momentum.
Value investorWeak fitThe company lacks current earnings, making it unsuitable for traditional value metrics.
Dividend investorWeak fitArvinas provides no dividend income and is not expected to do so for the foreseeable future.
Low-risk investorWeak fitClinical-stage biotech investments carry inherent high risk and volatility.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical data outcomes frequently cause sharp, unpredictable stock price swings.
Valuation riskHighValuations are speculative, based on future clinical success and long-term market potential.
Competition risk (protein degradation platforms)Medium / highNumerous well-funded entities are racing to develop competing degradation technologies.
Business qualityMediumWhile the technology is innovative, the lack of commercialized products limits current business quality metrics.
Dividend incomeLow / noneThe company does not provide income to shareholders.
Execution riskHighThe company must successfully navigate complex clinical trials and regulatory approval processes.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Moderately Choppy
PRICE STABILITY

Moderately Choppy

The stock has experienced noticeable price swings while retaining some directional structure.

Analysis of Past Performance

Type Stock
Historic Profit 0.01%
Avg. Invested days 28
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/28/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ARVN receives a 3-star rating, supported by solid company fundamentals, and strong analyst coverage. The rating is constrained by weak unit economics, and weak price momentum.

Company Fundamentals

★★★★★
ARVN has solid overall fundamentals (4 stars), with moderate financial health, solid growth momentum, and strong ownership. In FY2025 versus FY2024, strong earnings growth (+59.4%) is partially offset by weak cash generation (FCF margin -105.0%), slightly negative revenue growth (-0.3%), weak profitability (net margin -30.8%).

Financial Health Rating

★★★★★
ARVN's financial health is supported by solid liquidity, including working-capital and asset support (WC/assets 77.8%). Cash strength is soft (2 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is ARVN's strongest growth driver at +59.4% FY2025 versus FY2024 (strong, 5 stars). By comparison, while revenue growth (-0.3%, slightly negative) and free-cash-flow growth (-5.6%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 83.8% and approximately 88.1% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 7.80% supports management-shareholder alignment.

Top 5 Institutional Investors

BlackRock Inc 10.40%
Vanguard Portfolio Management, LLC 5.95%
D. E. Shaw & Co LP 5.35%
Pfizer Inc 5.29%
Vanguard Capital Management, LLC 4.11%

Unit Economics (Per $1K Revenue)

★★★★★
ARVN generates approximately $980 of gross profit, $-438 of operating income, and $-1,050 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Operating losses and cash burn explain the 1-star rating, with weak cash conversion and weak capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: -0.37% (Tax Credit)

Quantitative Style Profile

★★★★★
ARVN has a liquid profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

Value-OrientedHigh VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 489.72M USD
Price to earnings Ratio 29.19
1Y Target Price 13.93
Price to earnings Ratio 29.19
1Y Target Price 13.93
Volume (30-day avg) 769.8K shares
Beta 1.76
52 Weeks Range 6.97 - 14.51
Updated Date 09/27/2026
52 Weeks Range 6.97 - 14.51
Updated Date 09/27/2026
Dividends yield (FY) -
Basic EPS (TTM) 0.26

How Company Makes Money

Business areaWhat it includesRetail investor read
Collaboration and LicensingUpfront payments, development milestones, and royalties from partners like Pfizer and Bayer.Arvinas generates cash by selling rights to its technology to larger pharma firms to fund its own drug development.

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

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Valuation

Trailing PE 29.19
Forward PE 17.86
Enterprise Value -48.58M
Price to Sales(TTM) 1.55
Enterprise Value -48.58M
Price to Sales(TTM) 1.55
Enterprise Value to Revenue 0.03
Enterprise Value to EBITDA -1.62
Shares Outstanding 64.52M
Shares Floating 56.81M
Shares Outstanding 64.52M
Shares Floating 56.81M
Percent Insiders 7.8
Percent Institutions 83.75

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Arvinas Inc

Exchange NASDAQ
Headquarters New Haven, CT, United States
IPO Launch date 2018-09-27
CEO, President & Director Dr. Randy Teel Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 246
Full time employees 246

Arvinas, Inc., a clinical-stage biotechnology company, engages in the discovery, development, and commercialization of therapies to degrade disease-causing proteins. The company develops proteolysis targeting chimeras (PROTAC) targeted protein degraders that are designed to harness the body's own natural protein disposal system to degrade and remove disease-causing proteins. It is also developing clinical development programs , including ARV-102, a leucine-rich repeat kinase 2 (LRRK2) protein for the treatment of neurodegenerative diseases, such as Parkinson's disease and progressive supranuclear palsy; ARV-806, a Kirsten rat sarcoma, G12D protein for the treatment of cancers with the G12D mutation, comprising pancreatic, colorectal, and non-small cell lung cancer; ARV-393, a B-cell lymphoma 6 protein for the treatment of relapsed/refractory non-Hodgkin lymphoma (NHL); ARV-027, a polyglutamine-expanded androgen receptor in skeletal muscle; and vepdegestrant, an estrogen receptor for the treatment of locally advanced or metastatic ER+/HER2- breast cancer. In addition, the company develops Bavdegalutamide (ARV-110) and Luxdegalutamide (ARV-766), investigational orally bioavailable PROTAC protein degraders for the treatment of men with metastatic castration-resistant prostate cancer. It has collaborations with Pfizer Inc., Genentech, Inc., F. Hoffman-La Roche Ltd., Carrick Therapeutics Limited, and Bayer AG. The company was founded in 2013 and is based in New Haven, Connecticut.