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Cue Biopharma (CUE)

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Upturn Advisory Summary
12/16/2025: CUE (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $5
1 Year Target Price $5
| 2 | Strong Buy |
| 2 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -66.21% | Avg. Invested days 24 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 36.42M USD | Price to earnings Ratio - | 1Y Target Price 5 |
Price to earnings Ratio - | 1Y Target Price 5 | ||
Volume (30-day avg) 4 | Beta 1.4 | 52 Weeks Range 0.41 - 1.75 | Updated Date 12/15/2025 |
52 Weeks Range 0.41 - 1.75 | Updated Date 12/15/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.39 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) -351.05% |
Management Effectiveness
Return on Assets (TTM) -62.31% | Return on Equity (TTM) -195.19% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 25854151 | Price to Sales(TTM) 5.13 |
Enterprise Value 25854151 | Price to Sales(TTM) 5.13 | ||
Enterprise Value to Revenue 3.64 | Enterprise Value to EBITDA -1.76 | Shares Outstanding 78737736 | Shares Floating 78472390 |
Shares Outstanding 78737736 | Shares Floating 78472390 | ||
Percent Insiders 0.34 | Percent Institutions 22.94 |
About Cue Biopharma
Exchange NASDAQ | Headquaters Boston, MA, United States | ||
IPO Launch date 2018-01-02 | President & CEO Dr. Usman Azam M.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 41 | Website https://www.cuebiopharma.com |
Full time employees 41 | Website https://www.cuebiopharma.com | ||
Cue Biopharma, Inc., a clinical-stage biopharmaceutical company, develops a novel class of injectable therapeutics to selectively engage and modulate targeted, disease relevant T cells in the United States. Its lead drug product candidate is the CUE-401, a novel approach to induce and expand antigen specific Tregs for regulating disease causing autoreactive Teff cells which is in preclinical trial; and CUE-501, a treatment of autoimmune disease via anti-viral T cell-mediated depletion of B cells. The company also develops CUE-101, which is in phase 1b clinical trial to treat HPV+ recurrent metastatic, or head and neck squamous cell carcinoma in second line, and beyond patients as a monotherapy, as well as in phase 1b clinical trial for the treatment of head and neck squamous cell carcinoma as a first line, therapy in combination with standard of care KEYTRUDA; and CUE-102, which is in phase 1b clinical trial as a monotherapy in late line recurrent metastatic WT1+ colorectal, gastric, ovarian, and pancreatic cancer. It has collaboration agreements with LG Chem, Ltd. for the development of CUE-101 and CUE-102 Immuno-STATs; collaboration and option agreement with Ono Pharmaceutical Co., Ltd to development and commercialization rights for CUE-401; and license agreement with Albert Einstein College of Medicine. The company was formerly known as Imagen Biopharma, Inc. and changed its name to Cue Biopharma, Inc. in October 2016. Cue Biopharma, Inc. was incorporated in 2014 and is headquartered in Boston, Massachusetts.

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