Upturn unsubscribed user
$1.14/ day, billed weekly
Cancel anytime
(Ad-Free, Unlimited access)​
NO CREDIT CARD REQUIRED
DMAC logo DMAC
Upturn stock ratingUpturn stock rating
DMAC logo

DiaMedica Therapeutics Inc (DMAC)

Upturn stock ratingUpturn stock rating
$3.84
Last Close (24-hour delay)
upturn advisory
PASS
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock infoUpturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

06/27/2025: DMAC (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

rating

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

rating

4 Analysts rated it

Limited analyst coverage, niche firm, research info may be scarce.

1 Year Target Price $9.67

1 Year Target Price $9.67

Analysts Price Target For last 52 week
$9.67Target price
Low$2.8
Current$3.84
high$6.82

Analysis of Past Performance

Type Stock
Historic Profit 31.02%
Avg. Invested days 42
Today’s Advisory PASS
Upturn Star Rating Upturn stock ratingUpturn stock rating
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulationUpturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulationUpturn Profits based on simulation Last Close 06/27/2025

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 167.25M USD
Price to earnings Ratio -
1Y Target Price 9.67
Price to earnings Ratio -
1Y Target Price 9.67
Volume (30-day avg) 4
Beta 1.2
52 Weeks Range 2.80 - 6.82
Updated Date 07/1/2025
52 Weeks Range 2.80 - 6.82
Updated Date 07/1/2025
Dividends yield (FY) -
Basic EPS (TTM) -0.65

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -41.27%
Return on Equity (TTM) -67.25%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 131241513
Price to Sales(TTM) -
Enterprise Value 131241513
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.96
Shares Outstanding 42883500
Shares Floating 24338082
Shares Outstanding 42883500
Shares Floating 24338082
Percent Insiders 26.28
Percent Institutions 35.99

Analyst Ratings

Rating 2
Target Price 9.67
Buy 1
Strong Buy 3
Buy 1
Strong Buy 3
Hold -
Sell -
Strong Sell -
Strong Sell -

ai summary icon Upturn AI SWOT

DiaMedica Therapeutics Inc

stock logo

Company Overview

overview logo History and Background

DiaMedica Therapeutics Inc. was founded in 2004. It is a clinical-stage biopharmaceutical company focused on developing novel treatments for neurological and kidney diseases. The company's lead product candidate is DM199.

business area logo Core Business Areas

  • Neurological Diseases: Developing DM199 for acute ischemic stroke (AIS) and other neurological conditions.
  • Kidney Diseases: Investigating DM199 for the treatment of chronic kidney disease (CKD).
  • DM199 Development: Researching and developing DM199, a recombinant human tissue kallikrein-1 (KLK1) protein.

leadership logo Leadership and Structure

Rick Pauls is the Chief Executive Officer. The company has a board of directors overseeing strategic direction. The organizational structure includes research and development, clinical operations, and administrative functions.

Top Products and Market Share

overview logo Key Offerings

  • DM199: DM199 is DiaMedica's lead product candidate currently in clinical trials for the treatment of acute ischemic stroke (AIS) and chronic kidney disease (CKD). Market share data is currently not available as the product is in development and not yet commercially available. Competitors include companies developing similar therapies for stroke and kidney diseases such as Boehringer Ingelheim, Genentech (Roche), and other biotechnology companies.

Market Dynamics

industry overview logo Industry Overview

The biopharmaceutical industry is highly competitive and research-intensive. Development of novel therapies for neurological and kidney diseases is a key area of focus. The industry is characterized by high risk, long development timelines, and significant regulatory hurdles.

Positioning

DiaMedica is positioning DM199 as a potentially differentiated therapy for stroke and kidney diseases, targeting a novel mechanism of action (KLK1 pathway). Their competitive advantage, if proven, would be superior efficacy or safety profiles. It is not yet well positioned in the market, because the treatment hasn't yet gone through the clinical trial phase.

Total Addressable Market (TAM)

The TAM for stroke and CKD therapies is substantial, estimated in the billions of dollars. DiaMedica is aiming to capture a portion of this market with DM199. Market Value is expected to be approximately $50 billion in the coming years.

Upturn SWOT Analysis

Strengths

  • Novel therapeutic approach targeting the KLK1 pathway
  • Potential to address unmet needs in stroke and kidney disease
  • Intellectual property protection for DM199
  • Experienced management team

Weaknesses

  • Dependence on successful clinical trial outcomes for DM199
  • Limited financial resources compared to larger pharmaceutical companies
  • Uncertainty regarding regulatory approval
  • No product currently generating revenue

Opportunities

  • Positive clinical trial results could lead to significant market value increase
  • Potential partnerships with larger pharmaceutical companies
  • Expansion into new indications for DM199
  • Growing prevalence of stroke and kidney disease

Threats

  • Failure of clinical trials
  • Competition from established therapies and other emerging treatments
  • Regulatory setbacks
  • Difficulty raising capital

Competitors and Market Share

competitor logo Key Competitors

  • LLY
  • NVO
  • SNY
  • GILD

Competitive Landscape

DiaMedica faces significant competition from larger pharmaceutical companies with established therapies and greater financial resources. Its success depends on demonstrating superior efficacy and safety of DM199.

Growth Trajectory and Initiatives

Historical Growth: Historical growth is characterized by development of DM199, progressing through clinical trials.

Future Projections: Future growth depends on successful completion of clinical trials and regulatory approval of DM199. Analyst estimates vary widely depending on clinical trial outcomes.

Recent Initiatives: Recent initiatives include advancing clinical trials for DM199 in AIS and CKD, and exploring potential partnerships.

Summary

DiaMedica Therapeutics is a clinical-stage biopharmaceutical company with potential, but faces high risk. The success of the company hinges on the successful clinical development and regulatory approval of DM199, its lead product candidate. It needs to secure additional funding to continue its clinical trials. The company should look out for failures of clinical trials, competition from established therapies and regulatory hurdles.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • SEC Filings
  • Company Website
  • Analyst Reports (where available)

Disclaimers:

This analysis is based on available information and does not constitute financial advice. Investment decisions should be based on independent research and consultation with a qualified financial advisor. Market share data are estimates and may not be precise.

Upturn AI SummarizationUpturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI SummarizationUpturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI SummarizationUpturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI SummarizationUpturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About DiaMedica Therapeutics Inc

Exchange NASDAQ
Headquaters Minneapolis, MN, United States
IPO Launch date 2008-01-04
President, CEO & Director Mr. Dietrich John Pauls MBA
Sector Healthcare
Industry Biotechnology
Full time employees 27
Full time employees 27

DiaMedica Therapeutics Inc., a clinical stage biopharmaceutical company, focuses on improving the lives of people suffering from severe ischemic diseases. Its lead candidate is DM199, a pharmaceutically active recombinant form of the human tissue kallikrein-1 protein, which is in Phase 2/3 trials for the treatment of acute ischemic stroke, as well as in Phase 2 to treat preeclampsia, cardio renal disease, and fetal growth restriction. The company also develops DM300, which is a recombinant human ulinastatin in the preclinical stage for the treatment of inflammatory diseases, such as acute pancreatitis. The company was formerly known as DiaMedica Inc. and changed its name to DiaMedica Therapeutics Inc. in December 2016. DiaMedica Therapeutics Inc. was incorporated in 2000 and is headquartered in Minneapolis, Minnesota.