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Elicio Therapeutics Inc.(ELTX)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$1.92
10/02/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Advisory Performance History (Simulated)Advisory Performance History info

Upturn Advisory & Investor View for ELTX

10/02/2026: ELTX (1-star) is currently NOT-A-BUY. Pass it for now.

Elicio Therapeutics is a clinical-stage biotechnology company focused on developing cancer vaccines through its proprietary Amphiphile (AMP) platform. Its core investment story centers on the potential of this technology to improve immunotherapy effectiveness by targeting lymph nodes, specifically for hard-to-treat KRAS-mutated tumors. While the company has a unique clinical approach, it faces high execution risks, lacks recurring revenue, and is currently dependent on outside financing to fund its operations. Investors should closely monitor clinical trial outcomes for the ELI-002 vaccine and any potential pharmaceutical partnerships. This stock is best suited for high-risk growth investors comfortable with the significant volatility common in early-stage biotech investments.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThe company offers high-growth potential via its platform but lacks the revenue base typically sought by growth investors.
Momentum investorMixed fitMomentum fit is conditional on positive clinical data readouts driving stock price volatility.
Value investorWeak fitThe company lacks current earnings or tangible assets, making traditional value metrics inapplicable.
Dividend investorWeak fitThe company is a cash-burning biotech that does not pay dividends.
Low-risk investorWeak fitThe company involves extreme risks associated with early-stage clinical development and potential total loss of capital.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighClinical-stage stocks are prone to extreme price swings based on trial results and regulatory updates.
Valuation riskMedium / highValuation is speculative and heavily dependent on long-term clinical success.
Competition risk (Immunotherapy)HighWell-funded competitors are also working on cancer vaccines, creating significant competitive pressure.
Business qualityMediumThe business is dependent on a specific, unproven technology platform.
Dividend incomeLow / noneThe company does not generate the cash flow necessary to support dividend payments.
Execution riskHighSuccess requires perfect execution of complex, expensive, and unpredictable clinical trials.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -34.82%
Avg. Invested days 39
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 4.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 10/02/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
ELTX receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by weak unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

★★★★★
ELTX has moderate overall fundamentals (3 stars), with moderate financial health, moderate growth momentum, and solid ownership. In FY2025 versus FY2024, solid earnings growth (+23.8%) is partially offset by soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%), soft profitability (net margin 0.0%).

Financial Health Rating

★★★★★
ELTX's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
Earnings growth is ELTX's strongest growth driver at +23.8% FY2025 versus FY2024 (solid, 4 stars). By comparison, while revenue growth (+0.0%, slightly negative) holds the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 16.2% and approximately 73.1% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 26.97% supports management-shareholder alignment.

Top 5 Institutional Investors

Knoll Capital Management LP 4.61%
BlackRock Inc 2.91%
Vanguard Capital Management, LLC 2.18%
Geode Capital Management, LLC 1.18%
State Street Corp 0.68%

Unit Economics (Per $1K Revenue)

★★★★★
ELTX generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Weak margins explain the 1-star rating, with weak cash conversion and strong capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: 0.00%

Quantitative Style Profile

★★★★★
ELTX has a liquid profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 50.46M USD
Price to earnings Ratio -
1Y Target Price 13.67
Price to earnings Ratio -
1Y Target Price 13.67
Volume (30-day avg) 347.1K shares
Beta 1.86
52 Weeks Range 1.71 - 16.00
Updated Date 10/02/2026
52 Weeks Range 1.71 - 16.00
Updated Date 10/02/2026
Dividends yield (FY) -
Basic EPS (TTM) -2.11

How Company Makes Money

Business areaWhat it includesRetail investor read
Clinical Research and DevelopmentResearching and developing the AMP platform and vaccine candidates.The company currently makes no money and loses cash while testing its medicines in clinical trials.
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 39.68M
Price to Sales(TTM) -
Enterprise Value 39.68M
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -2.61
Shares Outstanding 26.28M
Shares Floating 19.20M
Shares Outstanding 26.28M
Shares Floating 19.20M
Percent Insiders 26.97
Percent Institutions 16.25

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Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Elicio Therapeutics Inc.

Exchange NASDAQ
Headquarters Boston, MA, United States
IPO Launch date 2021-02-05
CEO, President & Director Mr. Robert T. Connelly
Sector Healthcare
Industry Biotechnology
Full time employees 33
Full time employees 33

Elicio Therapeutics, Inc., a clinical-stage biotechnology company, develops immunotherapies for the treatment of cancer. Its lead product candidate, ELI-002, is a multivalent lymph node-targeted amphiphile (AMP) peptide vaccine that is in Phase II clinical trials for seven Kirsten rat sarcoma viral oncogene homolog driver mutations. The company also develops ELI-007, a multivalent lymph node-targeted AMP peptide treatment for mutant b-raf murine sarcoma viral oncogene homolog B1-(BRAF) driven cancers, and ELI-008, a multivalent lymph node-targeted AMP peptide vaccine in preclinical studies for the treatment of mutated tumor protein p53-expressing cancers. Elicio Therapeutics, Inc. is headquartered in Boston, Massachusetts.