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Genprex Inc(GNPX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for GNPX
10/23/2026: GNPX (1-star) is currently NOT-A-BUY. Pass it for now.
Genprex Inc is a clinical-stage biotechnology company developing gene therapies for cancer and diabetes using its proprietary Oncoprex delivery system. The company's primary investment story centers on the potential of its lead candidate, Reqorsa, to improve outcomes in difficult-to-treat cancers. However, Genprex is currently pre-revenue and faces significant risks, including clinical trial uncertainty, high execution hurdles, and the need for frequent dilutive capital raises. It is a highly speculative, high-volatility stock primarily suited for aggressive investors with a high risk tolerance. Potential investors should monitor clinical trial progress and the company's cash runway as key indicators of long-term viability.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Weak fit | The company is early-stage with no revenue, representing high-risk speculative growth rather than established growth. |
| Momentum investor | Mixed fit | Momentum may be present during clinical trial updates, but requires a positive technical signal. |
| Value investor | Weak fit | The company lacks the earnings or cash flow history required for value-based investment strategies. |
| Dividend investor | Weak fit | Genprex does not pay dividends and is not suitable for income-focused investors. |
| Low-risk investor | Weak fit | The high volatility and clinical risk profile make this unsuitable for low-risk portfolios. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | Biotech stocks are highly sensitive to clinical news and funding developments. |
| Valuation risk | High | Valuation is speculative and heavily dependent on future trial success. |
| Competition risk (Large pharma) | High | Well-funded competitors have superior resources to develop and market competing therapies. |
| Business quality | Medium | The company holds promising intellectual property, but lacks a proven commercial franchise. |
| Dividend income | Low / none | The company does not generate the cash flow required for dividends. |
| Execution risk | High | The complexity of gene therapy development introduces significant risk of trial failure. |
Price Behavior
Steep Decline
The stock price has dropped sharply with strong downward pressure.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit 0% | Avg. Invested days 0 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  1.0 | Stock Returns Performance  1.0 |
| Profits based on simulation | Last Close 10/23/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.48M USD | Price to earnings Ratio - | 1Y Target Price 7.5 |
Price to earnings Ratio - | 1Y Target Price 7.5 | ||
Volume (30-day avg) 254.3K shares | Beta -0.97 | 52 Weeks Range 1.79 - 217.60 | Updated Date 10/23/2026 |
52 Weeks Range 1.79 - 217.60 | Updated Date 10/23/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -9.35 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Gene Therapy Development | Research and clinical trial advancement of Reqorsa and diabetes candidates. | The company currently burns cash to fund research and does not yet earn revenue from sales. |
Valuation
Trailing PE - | Forward PE - | Enterprise Value -12.36M | Price to Sales(TTM) - |
Enterprise Value -12.36M | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA 0.18 | Shares Outstanding 819.71K | Shares Floating 818.72K |
Shares Outstanding 819.71K | Shares Floating 818.72K | ||
Percent Insiders 0.21 | Percent Institutions 1.73 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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