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Maze Therapeutics, Inc. Common Stock (MAZE)

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Upturn Advisory Summary
01/09/2026: MAZE (3-star) is a STRONG-BUY. BUY since 85 days. Simulated Profits (151.69%). Updated daily EoD!
1 Year Target Price $47.33
1 Year Target Price $47.33
| 3 | Strong Buy |
| 1 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 120.96% | Avg. Invested days 41 | Today’s Advisory Regular Buy |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 1.87B USD | Price to earnings Ratio - | 1Y Target Price 47.33 |
Price to earnings Ratio - | 1Y Target Price 47.33 | ||
Volume (30-day avg) 4 | Beta - | 52 Weeks Range 6.71 - 43.29 | Updated Date 01/9/2026 |
52 Weeks Range 6.71 - 43.29 | Updated Date 01/9/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -2.56 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -27.37% | Return on Equity (TTM) -52.69% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 1514500343 | Price to Sales(TTM) 3.14 |
Enterprise Value 1514500343 | Price to Sales(TTM) 3.14 | ||
Enterprise Value to Revenue 369.01 | Enterprise Value to EBITDA 6.71 | Shares Outstanding 48119444 | Shares Floating 27045534 |
Shares Outstanding 48119444 | Shares Floating 27045534 | ||
Percent Insiders 1.88 | Percent Institutions 86.41 |
Upturn AI SWOT
Maze Therapeutics, Inc. Common Stock

Company Overview
History and Background
Maze Therapeutics, Inc. is a biopharmaceutical company founded in 2019. It focuses on developing precision therapeutics for genetically defined diseases. The company leverages its proprietary 'CellMaze' platform to identify and validate novel drug targets and develop personalized medicines. Significant milestones include the establishment of its platform, early-stage research programs, and strategic collaborations.
Core Business Areas
- Precision Therapeutics Discovery: Utilizing the CellMaze platform to identify novel therapeutic targets and drug candidates for genetically defined diseases. This involves advanced genomic and cellular profiling to understand disease mechanisms at a molecular level.
- Drug Development: Advancing identified drug candidates through preclinical and clinical development, aiming to bring novel treatments to patients with specific genetic profiles.
- Genomic Medicine: Focusing on the intersection of genomics and therapeutics to create personalized treatment strategies.
Leadership and Structure
Maze Therapeutics is led by a management team with expertise in genomics, drug discovery, and clinical development. The company is structured around its research and development functions, with a strong emphasis on its scientific platform and pipeline advancement.
Top Products and Market Share
Key Offerings
- Unnamed Pipeline Programs: Maze Therapeutics has several preclinical programs targeting various genetic diseases. Specific product names and detailed market share data are not publicly available at this early stage of development. Competitors would include other biotech companies focused on gene therapy, rare diseases, and precision medicine, such as Vertex Pharmaceuticals (VRTX), Moderna (MRNA), and Blueprint Medicines (BPMC).
Market Dynamics
Industry Overview
The biopharmaceutical industry, particularly the precision medicine and rare disease segments, is experiencing rapid growth. Advances in genomics, gene editing, and computational biology are enabling the development of highly targeted therapies. The market is characterized by significant R&D investment, complex regulatory pathways, and a growing demand for personalized treatments.
Positioning
Maze Therapeutics is positioned as an early-stage innovator in precision therapeutics. Its competitive advantage lies in its proprietary CellMaze platform, which aims to accelerate the identification and validation of drug targets for genetically defined diseases. The company operates in a highly competitive but also rapidly expanding niche within the broader pharmaceutical market.
Total Addressable Market (TAM)
The TAM for precision therapeutics and genetically defined diseases is substantial and growing. While specific figures for Maze's target areas are proprietary, the global rare disease market alone is projected to reach hundreds of billions of dollars in the coming years. Maze Therapeutics is positioned to address a portion of this TAM by focusing on specific genetic underpinnings of diseases where its platform can offer novel solutions.
Upturn SWOT Analysis
Strengths
- Proprietary CellMaze platform for target identification and validation
- Focus on genetically defined diseases with unmet needs
- Experienced leadership team in genomics and drug development
- Potential for highly personalized and effective therapies
Weaknesses
- Early-stage company with no approved products
- Reliance on successful pipeline development
- Significant R&D costs and long development timelines
- Limited public financial data due to its private or early-stage status
Opportunities
- Growing market for precision medicine and rare disease treatments
- Potential for strategic partnerships with larger pharmaceutical companies
- Advancements in genomics and related technologies
- Expansion into new therapeutic areas based on platform capabilities
Threats
- High risk and failure rates in drug development
- Intense competition from established and emerging biotech companies
- Evolving regulatory landscape for novel therapies
- Challenges in patient recruitment for clinical trials
- Funding risks for early-stage biotechnology companies
Competitors and Market Share
Key Competitors
- Vertex Pharmaceuticals (VRTX)
- Moderna (MRNA)
- Blueprint Medicines (BPMC)
- CRISPR Therapeutics (CRSP)
Competitive Landscape
Maze Therapeutics faces a competitive landscape with established biopharmaceutical companies and emerging biotech firms. Its advantage lies in its specialized platform and focus on genetically defined diseases. However, competitors often have larger R&D budgets, established manufacturing and commercialization capabilities, and diversified pipelines.
Growth Trajectory and Initiatives
Historical Growth: Historical growth for Maze Therapeutics is primarily in terms of expanding its scientific team, advancing its proprietary platform, and building its early-stage pipeline. This has likely been supported by significant investment from venture capital.
Future Projections: Future projections are highly speculative and depend on the successful development of its pipeline candidates and the efficacy of its CellMaze platform. Analysts would focus on potential market penetration for specific genetic diseases and the company's ability to navigate clinical trials and regulatory approvals.
Recent Initiatives: Recent initiatives likely include ongoing research and development for its lead pipeline programs, potential expansion of its scientific collaborations, and efforts to secure further funding for preclinical and clinical development.
Summary
Maze Therapeutics is an early-stage biopharmaceutical company with a promising proprietary platform for precision therapeutics. Its strengths lie in its innovative technology and focus on unmet medical needs in genetically defined diseases. However, as a pre-revenue company, it faces significant risks associated with drug development timelines, high R&D costs, and intense competition. Continued success will depend on robust pipeline development, successful clinical trials, and securing substantial funding.
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Sources and Disclaimers
Data Sources:
- Company press releases (where available)
- Biotechnology industry analysis reports
- Financial news outlets
- Scientific publications (for platform understanding)
Disclaimers:
This analysis is based on publicly available information and general industry knowledge. As Maze Therapeutics, Inc. is an early-stage company, much of the detailed financial and operational data is not publicly disclosed. This information is for informational purposes only and does not constitute financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Maze Therapeutics, Inc. Common Stock
Exchange NASDAQ | Headquaters South San Francisco, CA, United States | ||
IPO Launch date 2025-01-31 | CEO & Director Dr. Jason V. Coloma M.B.A., M.P.H., Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 125 | Website https://www.mazetx.com |
Full time employees 125 | Website https://www.mazetx.com | ||
Maze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of renal, cardiovascular, related metabolic diseases, and obesity in the United States. Its lead programs include MZE829, an oral small molecule inhibitor of apolipoprotein L1, or APOL1, which is in phase II clinical trial for the treatment of patients with APOL1 kidney disease; and MZE782, an oral small molecule inhibitor of the solute transporter SLC6A19, which is in phase I clinical trial for the treatment of chronic kidney disease. The company also offers MZE001, a clinical program for the treatment of Pompe disease. Maze Therapeutics, Inc. was formerly known as Modulus Therapeutics, Inc. and changed its name to Maze Therapeutics, Inc. in September 2018. The company was incorporated in 2017 and is based in South San Francisco, California.

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