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Nanobiotix (NBTX)



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Upturn Advisory Summary
09/16/2025: NBTX (2-star) has a low Upturn Star Rating. Not recommended to BUY.
1 Year Target Price $7.69
1 Year Target Price $7.69
3 | Strong Buy |
0 | Buy |
1 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit 110.94% | Avg. Invested days 41 | Today’s Advisory Consider higher Upturn Star rating |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 480.17M USD | Price to earnings Ratio - | 1Y Target Price 7.69 |
Price to earnings Ratio - | 1Y Target Price 7.69 | ||
Volume (30-day avg) 4 | Beta 1.58 | 52 Weeks Range 2.76 - 10.59 | Updated Date 09/16/2025 |
52 Weeks Range 2.76 - 10.59 | Updated Date 09/16/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -1.62 |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Earnings Date
Report Date 2025-09-17 | When After Market | Estimate -0.3529 | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) 271.42% |
Management Effectiveness
Return on Assets (TTM) -52.89% | Return on Equity (TTM) -198.69% |
Valuation
Trailing PE - | Forward PE 48.31 | Enterprise Value 472000708 | Price to Sales(TTM) 3.82 |
Enterprise Value 472000708 | Price to Sales(TTM) 3.82 | ||
Enterprise Value to Revenue 3.39 | Enterprise Value to EBITDA -2.45 | Shares Outstanding 47921000 | Shares Floating 24806897 |
Shares Outstanding 47921000 | Shares Floating 24806897 | ||
Percent Insiders - | Percent Institutions 11.9 |
Upturn AI SWOT
Nanobiotix

Company Overview
History and Background
Nanobiotix S.A. was founded in 2003. It is a late-stage clinical biotechnology company pioneering physics-based approaches to expand cancer treatment possibilities. They focus on enhancing the effectiveness of radiotherapy.
Core Business Areas
- NBTXR3 Development: Development and clinical trials for NBTXR3, their lead product candidate, to enhance radiotherapy effectiveness in various cancer types.
- Research and Development: Ongoing research and development activities to explore new applications and formulations of their nanotechnology-based therapies.
- Partnerships and Licensing: Establishing partnerships and licensing agreements with pharmaceutical companies for the commercialization of NBTXR3.
Leadership and Structure
The leadership team consists of key executives in areas such as research and development, clinical operations, and commercialization. The organizational structure is focused on drug development and clinical trials.
Top Products and Market Share
Key Offerings
- NBTXR3: NBTXR3 is Nanobiotix's lead product candidate, a nanoparticle designed to enhance the effectiveness of radiotherapy. Currently in clinical trials for multiple cancer types. Market share is not yet applicable as NBTXR3 is not yet approved and commercially available. Competitors depend on cancer type and radiation enhancing agent such as conventional chemotherapy and other pharmaceutical drugs.
Market Dynamics
Industry Overview
The oncology market is a large and growing market, with increasing demand for more effective and less toxic cancer treatments. The radiotherapy enhancement market is an emerging niche within the broader oncology market.
Positioning
Nanobiotix aims to establish itself as a leader in the radiotherapy enhancement market with NBTXR3, offering a novel physics-based approach to improving cancer treatment outcomes. Nanobiotix's competative advantage are the novel treatment approach and clinical progress.
Total Addressable Market (TAM)
The TAM for radiotherapy enhancement is estimated to be in the billions of dollars. Nanobiotix is positioned to capture a significant share of this market with successful clinical trials and regulatory approvals.
Upturn SWOT Analysis
Strengths
- Novel technology platform
- Promising clinical trial results
- Strong intellectual property portfolio
- Experienced management team
Weaknesses
- Reliance on single product candidate (NBTXR3)
- High development costs
- Regulatory approval risks
- Commercialization challenges
Opportunities
- Expansion into new cancer types
- Partnerships with major pharmaceutical companies
- Regulatory approvals in key markets
- Advancements in nanotechnology
Threats
- Competition from established cancer treatments
- Failure of clinical trials
- Adverse regulatory decisions
- Economic downturn
Competitors and Market Share
Key Competitors
- Varian Medical Systems(Siemens Healthineers)
- Elekta AB
- Merck (MRK)
Competitive Landscape
Nanobiotix competes with established cancer treatment modalities such as surgery, chemotherapy, and radiation therapy. Its advantage lies in enhancing the effectiveness of radiotherapy with a physics based approach.
Growth Trajectory and Initiatives
Historical Growth: Nanobiotix's historical growth has been driven by the advancement of NBTXR3 through clinical trials.
Future Projections: Future growth is projected to be driven by regulatory approvals, commercialization of NBTXR3, and expansion into new indications.
Recent Initiatives: Recent initiatives include ongoing clinical trials, regulatory submissions, and partnership discussions.
Summary
Nanobiotix is a clinical-stage biotechnology company with a novel approach to enhancing radiotherapy. The company's future relies heavily on the successful development and commercialization of NBTXR3. While promising clinical trial results offer substantial opportunity, regulatory hurdles and competition from established treatments present significant challenges. Investors should carefully monitor clinical trial outcomes and regulatory progress.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Nanobiotix website
- Company press releases
- Analyst reports
- SEC filings
Disclaimers:
The information provided is for informational purposes only and should not be considered investment advice. Investment decisions should be made based on individual research and consultation with a qualified financial advisor.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Nanobiotix
Exchange NASDAQ | Headquaters - | ||
IPO Launch date 2020-12-11 | Co-Founder, President of the Executive Board & CEO Mr. Laurent Levy Ph.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 108 | Website https://www.nanobiotix.com |
Full time employees 108 | Website https://www.nanobiotix.com |
Nanobiotix S.A. operates as a clinical-stage biotechnology that focuses on developing product candidates for the treatment of cancer and other unmet medical needs. Its lead product candidate is NBTXR3, a sterile aqueous suspension of crystalline hafnium oxide nanoparticles used for the treatment of soft tissue sarcoma, head and neck cancers, liver cancers, prostate cancer, pancreatic cancer, esophageal cancer, rectal cancer, and non-small cell lung cancer. The company has a partnership with Lian Oncology Limited to develop and commercialize NBTXR3 in Greater China, South Korea, Singapore, and Thailand. Nanobiotix S.A. was incorporated in 2003 and is based in Paris, France.

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