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Upturn AI Summary - About
Vaxcyte Inc(PCVX)
Advisory History & Simulated Performance *
*as per simulation (see disclosures)- ALL
- 1Y
- 1M
- 1W
- BUY Advisory
- SELL Advisory (Profit)
- SELL Advisory (Loss)
- Profit
- Loss
- PASS (Skip)
Stock price based on last close Advisory Performance History (Simulated)
Upturn Advisory & Investor View for PCVX
11/10/2026: PCVX (1-star) is currently NOT-A-BUY. Pass it for now.
Vaxcyte Inc is a clinical-stage biotechnology company developing advanced protein vaccines, primarily targeting the competitive pneumococcal disease market. Its core strength lies in its proprietary cell-free synthesis platform, which allows for broader, more precise vaccine coverage than legacy products. The investment story centers on the potential for its vaccine candidates, VAX-24 and VAX-31, to challenge market leaders. Key risks include intense competition from established pharmaceutical giants, significant clinical development hurdles, and the need for ongoing capital to fund operations. This stock is best suited for growth-oriented investors with a high risk tolerance who are closely monitoring clinical trial milestones and regulatory progress.
How to Read the Upturn Advisory
The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.
Company fundamentals, valuation, risks, and news provide supporting context about the business.
Investor Fit
| Investor style | Fit | Why |
|---|---|---|
| Growth investor | Strong fit | Vaxcyte offers high-upside exposure to the biotechnology sector contingent on clinical success. |
| Momentum investor | Mixed fit | Momentum is highly dependent on clinical trial outcomes and news flow. |
| Value investor | Weak fit | The company is not currently profitable and lacks traditional valuation metrics. |
| Dividend investor | Weak fit | The company does not pay dividends and reinvests all capital into research. |
| Low-risk investor | Weak fit | Biotechnology development carries high clinical and regulatory risks. |
Risk Profile
| Risk factor | Level | Why it matters |
|---|---|---|
| Price volatility | High | The stock price is highly sensitive to clinical trial announcements and FDA updates. |
| Valuation risk | Medium / high | Valuations are driven by future potential rather than current earnings. |
| Competition risk (Large Pharma) | High | Established incumbents have significant resources and entrenched distribution channels. |
| Business quality | Medium | The company has a proprietary platform but is still in the experimental development phase. |
| Dividend income | Low / none | Investors should not expect income from this investment. |
| Execution risk | High | Success depends on meeting complex clinical endpoints and regulatory requirements. |
Price Behavior
Strong Uptrend
The stock has maintained a strong upward price trend across the last three quarters.
Extreme Price Shocks
The stock has experienced exceptionally large and disruptive price movements during the period.
Analysis of Past Performance
Type Stock | Historic Profit 42.93% | Avg. Invested days 40 | Today’s Advisory PASS |
Upturn Advisory Rating  | Upturn Advisory Performance  2.0 | Stock Returns Performance  3.0 |
| Profits based on simulation | Last Close 11/10/2026 |
Upturn Scorecard
Upturn Star Rating 
Company Fundamentals
Financial Health Rating
Growth Momentum Score
Ownership
Top 5 Institutional Investors
Unit Economics (Per $1K Revenue)
Economic Dimensions
Quantitative Style Profile
Style Classification
Quality Focused
Key Highlights
Company Size Large-Cap Stock | Market Capitalization 10.69B USD | Price to earnings Ratio - | 1Y Target Price 117.2 |
Price to earnings Ratio - | 1Y Target Price 117.2 | ||
Volume (30-day avg) 3.2M shares | Beta 1.29 | 52 Weeks Range 42.40 - 90.75 | Updated Date 11/10/2026 |
52 Weeks Range 42.40 - 90.75 | Updated Date 11/10/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -8.05 |
How Company Makes Money
| Business area | What it includes | Retail investor read |
|---|---|---|
| Vaccine Development | Research, development, and eventual commercialization of pneumococcal protein vaccines. | The company is currently spending money to invent vaccines and does not yet have sales. |
Analyzing Revenue: Products, Geography and Growth
Revenue by Products
Product revenue - Year on Year
Valuation
Trailing PE - | Forward PE - | Enterprise Value 9.04B | Price to Sales(TTM) - |
Enterprise Value 9.04B | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -14.43 | Shares Outstanding 158.30M | Shares Floating 145.89M |
Shares Outstanding 158.30M | Shares Floating 145.89M | ||
Percent Insiders 0.47 | Percent Institutions 110.96 |
Financial Metrics
🧭 Investment Snapshot
Total Revenue (Scale)
Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.
Net Income (Profit)
Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.
Free Cash Flow (Cash Strength)
Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.
📈 Growth & Strength
Operating Income (Core Profit)
Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.
EBITDA (Cash Earnings)
Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.
Gross Profit (Unit Profitability)
Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.
🛡️ Financial Safety
Cash (Liquidity Buffer)
Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.
Total Debt (Leverage Risk)
Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.
Net Working Capital (Short-Term Health)
Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.
🧱 Balance Sheet Strength
Stockholder Equity (Net Worth)
Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.
Total Assets (Asset Base)
The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.
Income Before Tax (Pre-Tax Earnings)
Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.
⚙️ Cost & Drag Factors
Cost of Revenue (Production Cost)
Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.
Total Operating Expenses (Operating Cost)
Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.
Income Tax Expense (Tax Drag)
Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.
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