Upturn unsubscribed user
$1.14/ day, billed weekly
Cancel anytime
(Ad-Free, Unlimited access)​
NO CREDIT CARD REQUIRED
PCVX logo PCVX
Upturn stock rating
PCVX logo

Vaxcyte Inc (PCVX)

Upturn stock rating
$42.9
Last Close (24-hour delay)
Profit since last BUY19.1%
upturn advisory
Strong Buy
BUY since 15 days
  • BUY Advisory
  • SELL Advisory (Profit)​
  • SELL Advisory (Loss)​
  • Profit
  • Loss
  • Pass (Skip investing)
Upturn Stock info Stock price based on last close
*as per simulation
(see disclosures)
Time period over
  • ALL
  • YEAR
  • MONTH
  • WEEK

Upturn Advisory Summary

10/20/2025: PCVX (3-star) is a STRONG-BUY. BUY since 15 days. Simulated Profits (19.10%). Updated daily EoD!

Upturn Star Rating

rating

Moderate Performance

These Stocks/ETFs, based on Upturn Advisory, typically align with the market average, offering steady but unremarkable returns.

Number of Analysts

rating

10 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $98

1 Year Target Price $98

Analysts Price Target For last 52 week
$98 Target price
52w Low $27.66
Current$42.9
52w High $116

Analysis of Past Performance

Type Stock
Historic Profit 53.41%
Avg. Invested days 41
Today’s Advisory Strong Buy
Upturn Star Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance 3.0
Stock Returns Performance Upturn Returns Performance 3.0
Upturn Profits based on simulation Profits based on simulation
Upturn Profits based on simulation Last Close 10/20/2025

Key Highlights

Company Size Mid-Cap Stock
Market Capitalization 5.50B USD
Price to earnings Ratio -
1Y Target Price 98
Price to earnings Ratio -
1Y Target Price 98
Volume (30-day avg) 10
Beta 1.12
52 Weeks Range 27.66 - 116.00
Updated Date 10/20/2025
52 Weeks Range 27.66 - 116.00
Updated Date 10/20/2025
Dividends yield (FY) -
Basic EPS (TTM) -4.11

Analyzing Revenue: Products, Geography and Growth

Revenue by Products

Product revenue - Year on Year

Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -

Management Effectiveness

Return on Assets (TTM) -16.44%
Return on Equity (TTM) -21.65%

Valuation

Trailing PE -
Forward PE -
Enterprise Value 3634229236
Price to Sales(TTM) -
Enterprise Value 3634229236
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -14.43
Shares Outstanding 129823355
Shares Floating 116843616
Shares Outstanding 129823355
Shares Floating 116843616
Percent Insiders 0.65
Percent Institutions 117.45

ai summary icon Upturn AI SWOT

Vaxcyte Inc

stock logo

Company Overview

overview logo History and Background

Vaxcyte, Inc. (PCVX) is a clinical-stage vaccine innovation company revolutionizing the prevention of infectious diseases. Founded in 2013, it focuses on developing novel and improved vaccines to address current limitations in traditional vaccine approaches.

business area logo Core Business Areas

  • Pneumococcal Conjugate Vaccine (PCV) Candidates: Vaxcyte's primary focus is on developing PCV candidates, with its lead candidate, VAX24, targeting the 24 most prevalent pneumococcal serotypes to provide broader coverage than existing vaccines.

leadership logo Leadership and Structure

Grant Pickering serves as the CEO. The company has a typical biotech organizational structure with departments focused on R&D, clinical development, manufacturing, and commercialization.

Top Products and Market Share

overview logo Key Offerings

  • VAX24: VAX24 is Vaxcyte's lead PCV candidate. It is designed to improve upon existing PCVs like Pfizer's Prevnar 20 by targeting more serotypes. Prevnar 20 generated significant revenue. Competitors include Pfizer (PFE) and Merck (MRK).
  • VAX31: VAX31 is Vaxcyte's next-generation pneumococcal conjugate vaccine designed to cover 31 serotypes. Competitors include Pfizer (PFE) and Merck (MRK).
  • Vaxcyte's pipeline: Vaxcyte has a pipeline of innovative vaccine candidates targeting other infectious diseases, including those caused by Group A Strep (GAS) and Meningitis. Competitors depend on the infectious diseases targeted

Market Dynamics

industry overview logo Industry Overview

The vaccine market is experiencing growth due to increasing awareness of preventative healthcare, rising infectious disease prevalence, and technological advancements in vaccine development.

Positioning

Vaxcyte aims to differentiate itself through broader serotype coverage and improved immunogenicity compared to existing PCVs. Its competitive advantage lies in its X-vivo platform for vaccine development.

Total Addressable Market (TAM)

The global pneumococcal vaccine market is substantial, projected to reach billions of dollars annually. Vaxcyte aims to capture a significant share of this market with its PCV candidates.

Upturn SWOT Analysis

Strengths

  • Novel X-vivo platform technology
  • Experienced leadership team
  • Strong pipeline of vaccine candidates
  • Potentially broader serotype coverage compared to existing vaccines

Weaknesses

  • Clinical stage company with no currently marketed products
  • High dependence on clinical trial success
  • Significant R&D expenses
  • Intense competition from established players

Opportunities

  • Growing demand for pneumococcal vaccines
  • Potential to capture market share from existing vaccines
  • Expansion into new vaccine areas
  • Partnerships and collaborations

Threats

  • Clinical trial failures
  • Regulatory hurdles
  • Competition from established vaccine manufacturers
  • Patent challenges

Competitors and Market Share

competitor logo Key Competitors

  • PFE
  • MRK

Competitive Landscape

Vaxcyte faces strong competition from established players like Pfizer and Merck. Its competitive advantage relies on its next-generation vaccine candidates with broader coverage.

Growth Trajectory and Initiatives

Historical Growth: Vaxcyte's historical growth is characterized by the advancement of its vaccine candidates through preclinical and clinical stages.

Future Projections: Future growth is heavily dependent on successful clinical trial outcomes and regulatory approvals. Analyst estimates vary widely.

Recent Initiatives: Recent initiatives include the advancement of VAX24 into Phase 3 clinical trials and continued development of other pipeline candidates.

Summary

Vaxcyte is a clinical-stage company with innovative vaccine technology, particularly in pneumococcal vaccines. Success hinges on clinical trial results and regulatory approvals, facing competition from established pharmaceutical giants. Recent progress in clinical trials positions the company for potential future growth, but failure to obtain regulatory approval would be a major set back. They need to keep a close eye on cash burn to ensure enough runway.

Peer Comparison

Sources and Disclaimers

Data Sources:

  • Company filings
  • Analyst reports
  • Industry publications

Disclaimers:

This analysis is for informational purposes only and should not be considered investment advice. The data provided is based on publicly available information and may be subject to change.

Upturn AI Summarization AI Summarization is directionally correct and might not be accurate.

Upturn AI Summarization Summarized information shown could be a few years old and not current.

Upturn AI Summarization Fundamental Rating based on AI could be based on old data.

Upturn AI Summarization AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Vaxcyte Inc

Exchange NASDAQ
Headquaters San Carlos, CA, United States
IPO Launch date 2020-06-12
Co-Founder, CEO & Director Mr. Grant E. Pickering M.B.A.
Sector Healthcare
Industry Biotechnology
Full time employees 414
Full time employees 414

Vaxcyte, Inc., a clinical-stage vaccine innovation company, develops conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases. Its lead vaccine candidate is VAX-24, a 24-valent carrier-sparing investigational pneumococcal conjugate vaccine (PCV) for the prevention of invasive pneumococcal disease (IPD) in infants. The company also develops VAX-31, a 31-valent, carrier-sparing investigational PCV for the prevention of IPD in adults and children; VAX-A1, a novel conjugate vaccine candidate to prevent disease caused by Group A Streptococcus; VAX-PG, a novel protein vaccine candidate targeting the keystone pathogen responsible for periodontitis; and VAX-GI, a novel preclinical vaccine candidate for the treatment of dysentery and shigellosis, which is caused by Shigella bacteria. The company was formerly known as SutroVax, Inc. and changed its name to Vaxcyte, Inc. in May 2020. Vaxcyte, Inc. was incorporated in 2013 and is headquartered in San Carlos, California.