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Tharimmune Inc. (THAR)



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Upturn Advisory Summary
08/28/2025: THAR (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $5
1 Year Target Price $5
1 | Strong Buy |
0 | Buy |
0 | Hold |
0 | Sell |
0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -31.77% | Avg. Invested days 21 | Today’s Advisory PASS |
Upturn Star Rating ![]() ![]() | Upturn Advisory Performance ![]() | Stock Returns Performance ![]() |
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Key Highlights
Company Size Small-Cap Stock | Market Capitalization 31.92M USD | Price to earnings Ratio - | 1Y Target Price 5 |
Price to earnings Ratio - | 1Y Target Price 5 | ||
Volume (30-day avg) 1 | Beta 1.19 | 52 Weeks Range 0.95 - 9.08 | Updated Date 08/29/2025 |
52 Weeks Range 0.95 - 9.08 | Updated Date 08/29/2025 | ||
Dividends yield (FY) - | Basic EPS (TTM) -6.06 |
Earnings Date
Report Date 2025-08-14 | When - | Estimate - | Actual -0.64 |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -140.33% | Return on Equity (TTM) -340.26% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 29930204 | Price to Sales(TTM) - |
Enterprise Value 29930204 | Price to Sales(TTM) - | ||
Enterprise Value to Revenue - | Enterprise Value to EBITDA -6.32 | Shares Outstanding 5276440 | Shares Floating 3468558 |
Shares Outstanding 5276440 | Shares Floating 3468558 | ||
Percent Insiders 16.96 | Percent Institutions 1.48 |
Upturn AI SWOT
Tharimmune Inc.

Company Overview
History and Background
Tharimmune, Inc. is a clinical-stage biotechnology company focused on developing a pipeline of therapeutic candidates for autoimmune, inflammatory, and fibrotic diseases. The company was founded in 2016 and completed a merger with Mountain Crest Acquisition Corp. V, thus going public in 2023.
Core Business Areas
- Autoimmune Disease Therapies: Tharimmune develops therapies targeting autoimmune disorders, aiming to modulate the immune system and reduce inflammation.
- Inflammatory Disease Therapies: Tharimmune focuses on creating innovative treatments for inflammatory conditions, addressing the underlying causes of inflammation.
- Fibrotic Disease Therapies: Tharimmune is creating innovative treatments for fibrotic conditions, addressing the underlying causes of excessive tissue scarring.
Leadership and Structure
Tharimmune is led by a team with expertise in drug development and immunology. The company structure involves scientific advisory boards and partnerships with research institutions.
Top Products and Market Share
Key Offerings
- T109: T109 is Tharimmune's lead drug candidate for treating moderate to severe recurrent corneal erosion (RCE). Current treatments include lubrication and in severe cases surgery. Competitors include Dompe farmaceutici S.p.A. with Oxervate. Market share data for T109 is not yet available as it is still in clinical development.
- Other Pipeline Candidates: Tharimmune has several other preclinical candidates targeting inflammatory and fibrotic diseases. Market share data is not available for these preclinical candidates as they have not yet been commercialized.
Market Dynamics
Industry Overview
The biotechnology industry is characterized by intense research and development, high regulatory hurdles, and significant market competition. The market for autoimmune, inflammatory, and fibrotic disease treatments is substantial and growing.
Positioning
Tharimmune aims to differentiate itself through its innovative therapeutic approaches. Its ability to address significant unmet medical needs positions it for potential growth.
Total Addressable Market (TAM)
The global market for autoimmune, inflammatory, and fibrotic disease treatments is expected to reach hundreds of billions of dollars. Tharimmune is positioned to potentially capture a share of this market with successful product development.
Upturn SWOT Analysis
Strengths
- Innovative therapeutic pipeline
- Experienced leadership team
- Focus on unmet medical needs
Weaknesses
- Early-stage development risk
- Limited financial resources compared to larger competitors
- Reliance on clinical trial outcomes
Opportunities
- Positive clinical trial results
- Strategic partnerships and collaborations
- Expansion into new therapeutic areas
Threats
- Clinical trial failures
- Regulatory hurdles
- Competition from established pharmaceutical companies
Competitors and Market Share
Key Competitors
- LLY
- ABBV
- NVS
- SNY
- MRK
Competitive Landscape
Tharimmune faces significant competition from established pharmaceutical companies with greater resources and experience. Its success depends on differentiating itself through innovative technologies and effective clinical trial execution.
Growth Trajectory and Initiatives
Historical Growth: Historical growth is limited due to the company's recent emergence as a public entity after the merger.
Future Projections: Future growth is dependent on the successful development and commercialization of its therapeutic candidates. Analyst estimates are based on potential market opportunities.
Recent Initiatives: Recent initiatives include advancing T109 through clinical trials and expanding its research pipeline.
Summary
Tharimmune is an early-stage biotechnology firm with a focus on innovative therapies. Its future hinges on positive clinical trial outcomes. Weaknesses include limited financial resources and strong competition. The company needs to carefully manage its cash burn and secure strategic partnerships.
Peer Comparison
Sources and Disclaimers
Data Sources:
- Company Website
- SEC Filings
- Third-Party Market Research Reports
- Analyst Reports
Disclaimers:
This analysis is based on available information and is subject to change. It should not be considered financial advice.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Tharimmune Inc.
Exchange NASDAQ | Headquaters Bridgewater, NJ, United States | ||
IPO Launch date 2022-01-12 | CEO & Director Mr. Sireesh Appajosyula Pharm.D. | ||
Sector Healthcare | Industry Biotechnology | Full time employees 2 | Website https://www.tharimmune.com |
Full time employees 2 | Website https://www.tharimmune.com |
Tharimmune, Inc., a clinical-stage biotechnology company, engages in the development of therapeutic candidates for rare, inflammatory, and oncologic conditions with high unmet need in the United States. The company's pre-clinical immuno-oncology pipeline includes TH104, a product candidate for the treatment of liver-related and other pruritogenic inflammatory conditions; TH023 which is phase 1 clinical trial used to treat multiple high value autoimmune indications; and HS1940, which targets programmed cell death protein 1 (PD-1). It has a research collaboration and product license agreement with Minotaur Therapeutics, Inc. for the development of proprietary targeted biologics. The company was formerly known as Hillstream BioPharma, Inc. and changed its name to Tharimmune, Inc. in September 2023. Tharimmune, Inc. was incorporated in 2017 and is headquartered in Bridgewater, New Jersey.

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