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JANX 1-star rating from Upturn Advisory
Janux Therapeutics Inc (JANX) company logo

Janux Therapeutics Inc (JANX)

Janux Therapeutics Inc (JANX) 1-star rating from Upturn Advisory
$13.08
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PASS
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Upturn Advisory Summary

02/20/2026: JANX (1-star) is currently NOT-A-BUY. Pass it for now.

Upturn Star Rating

Upturn 1 star rating for performance

Not Recommended Performance

These Stocks/ETFs, based on Upturn Advisory, consistently fall short of market performance, signaling caution before investing.

Number of Analysts

3 star rating from financial analysts

13 Analysts rated it

Moderately tracked stock, growing coverage, gaining market and investor attention.

1 Year Target Price $63.71

1 Year Target Price $63.71

Analysts Price Target For last 52 week
$63.71 Target price
52w Low $12.12
Current$13.08
52w High $36.25
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Key Highlights

Company Size Small-Cap Stock
Market Capitalization 807.18M USD
Price to earnings Ratio -
1Y Target Price 63.71
Price to earnings Ratio -
1Y Target Price 63.71
Volume (30-day avg) 13
Beta 2.87
52 Weeks Range 12.12 - 36.25
Updated Date 02/20/2026
52 Weeks Range 12.12 - 36.25
Updated Date 02/20/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.67
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Earnings Date

Report Date -
When -
Estimate -
Actual -

Profitability

Profit Margin -
Operating Margin (TTM) -352.51%

Management Effectiveness

Return on Assets (TTM) -10.49%
Return on Equity (TTM) -12.48%

Valuation

Trailing PE -
Forward PE -
Enterprise Value -157946474
Price to Sales(TTM) 80.72
Enterprise Value -157946474
Price to Sales(TTM) 80.72
Enterprise Value to Revenue 972.59
Enterprise Value to EBITDA -33.8
Shares Outstanding 60147807
Shares Floating 40996745
Shares Outstanding 60147807
Shares Floating 40996745
Percent Insiders 7
Percent Institutions 107.75

Icon representing Upturn AI-generated SWOT analysis summary Upturn AI SWOT

Janux Therapeutics Inc

Janux Therapeutics Inc(JANX) company logo displayed in Upturn AI summary

Company Overview

Company history and background logo History and Background

Janux Therapeutics Inc. was founded in 2017 with a focus on developing innovative cancer therapies. The company's evolution has been driven by its proprietary tumor-targeted protein degrader platform, aiming to create next-generation therapeutics for difficult-to-treat cancers. Key milestones include the initiation of clinical trials and strategic collaborations.

Company business area logo Core Business Areas

  • Tumor-Targeted Protein Degraders: Janux Therapeutics develops novel protein degraders designed to specifically target cancer cells, leading to their destruction. This platform aims to address limitations of current therapies by offering greater precision and efficacy.

leadership logo Leadership and Structure

Janux Therapeutics is led by a team of experienced professionals in drug development, oncology, and business management. The organizational structure is typical of a biotechnology company, with research and development as a primary focus, supported by clinical operations, regulatory affairs, and corporate functions.

Top Products and Market Share

Product Key Offerings logo Key Offerings

  • Description: JANX001 is a novel tumor-targeted protein degrader currently in clinical development for various solid tumors. Specific market share data is not yet available due to its early-stage development. Competitors in the broader oncology drug market are numerous and include companies developing targeted therapies, immunotherapies, and chemotherapies. For protein degraders, competitors include companies like Arvinas and Kymera Therapeutics.
  • Product Name 1: JANX001

Market Dynamics

industry overview logo Industry Overview

The oncology therapeutics market is a rapidly growing and highly competitive sector driven by significant unmet medical needs and advancements in scientific understanding of cancer biology. The development of targeted therapies and novel modalities like protein degraders represents a key trend.

Positioning

Janux Therapeutics is positioned as an innovator in the emerging field of tumor-targeted protein degraders. Its proprietary platform offers a potential competitive advantage by enabling the development of highly specific and potent anti-cancer agents. However, as a clinical-stage company, it faces the inherent risks associated with drug development and faces intense competition from established pharmaceutical companies and other emerging biotech firms.

Total Addressable Market (TAM)

The total addressable market for oncology drugs is in the hundreds of billions of dollars globally. Janux Therapeutics, by focusing on specific cancer types and leveraging its unique platform, aims to capture a significant portion of the TAM for its therapeutic candidates as they advance through development and gain regulatory approval.

Upturn SWOT Analysis

Strengths

  • Proprietary tumor-targeted protein degrader platform
  • Experienced leadership team
  • Focus on addressing unmet needs in oncology
  • Potential for differentiated therapeutic approach

Weaknesses

  • Clinical-stage company with no approved products
  • Significant funding requirements for clinical development
  • Reliance on the success of a single platform technology
  • Early stage of product pipeline

Opportunities

  • Advancements in precision medicine
  • Increasing investment in oncology research and development
  • Potential for strategic partnerships and collaborations
  • Expansion into new indications and cancer types

Threats

  • Clinical trial failures or delays
  • Regulatory hurdles and approval processes
  • Intense competition from established and emerging companies
  • Pricing pressures and market access challenges
  • Intellectual property challenges

Competitors and Market Share

Key competitor logo Key Competitors

  • Arvinas Inc. (ARVN)
  • Kymera Therapeutics Inc. (KYMR)
  • Nurix Therapeutics Inc. (NRIX)

Competitive Landscape

Janux Therapeutics' advantages lie in its specific tumor-targeting approach within the protein degrader space. However, it faces competition from companies with more advanced pipelines, established clinical data, and greater financial resources. The competitive landscape is characterized by rapid innovation and the high risk associated with drug development.

Growth Trajectory and Initiatives

Historical Growth: Janux Therapeutics' growth trajectory has been focused on scientific advancement, platform development, and progress through preclinical and early-stage clinical development. Growth is measured by pipeline progression and the acquisition of R&D capabilities.

Future Projections: Future growth projections for Janux Therapeutics are contingent on the successful outcomes of its clinical trials, regulatory approvals, and potential commercialization of its drug candidates. Analyst estimates would typically focus on the potential market size and success probability of their pipeline assets.

Recent Initiatives: Recent initiatives likely include advancing JANX001 into later-stage clinical trials, exploring new applications for its protein degrader platform, and potentially seeking strategic partnerships or financing rounds to fund ongoing development.

Summary

Janux Therapeutics is a clinical-stage biotechnology company with a promising proprietary platform for developing tumor-targeted protein degraders. Its strengths lie in its innovative technology and experienced team, while its main weaknesses are its early stage of development and reliance on clinical success. Opportunities exist in the expanding oncology market and advancements in precision medicine, but threats include clinical trial failures and intense competition. The company needs to focus on achieving key clinical milestones and securing adequate funding to navigate the challenging drug development landscape.

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Sources and Disclaimers

Data Sources:

  • Company filings (SEC)
  • Financial news outlets
  • Biotechnology industry reports
  • Market research databases

Disclaimers:

This analysis is based on publicly available information and is for informational purposes only. It does not constitute investment advice. Investing in biotechnology stocks, especially clinical-stage companies, carries significant risk. Investors should conduct their own due diligence and consult with a qualified financial advisor before making any investment decisions.

Information icon for Upturn AI Summarization accuracy disclaimer AI Summarization is directionally correct and might not be accurate.

Information icon for Upturn AI Summarization data freshness disclaimer Summarized information shown could be a few years old and not current.

Information icon warning about Upturn AI Fundamental Rating based on potentially old data Fundamental Rating based on AI could be based on old data.

Information icon warning about potential inaccuracies or hallucinations in Upturn AI-generated summaries AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.

About Janux Therapeutics Inc

Exchange NASDAQ
Headquaters San Diego, CA, United States
IPO Launch date 2021-06-11
President, CEO & Director Dr. David Alan Campbell Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 109
Full time employees 109

Janux Therapeutics, Inc., a clinical stage biopharmaceutical company, develops immunotherapies based on Tumor Activated T Cell Engager (TRACTr) and Tumor Activated Immunomodulator (TRACIr) platforms technology to treat patients with cancer. Its clinical candidates include JANX007, a prostate-specific membrane antigen or PSMA-TRACTr, which is in Phase 1 clinical trial in adults for the treatment of metastatic castration-resistant prostate cancer and the vasculature of other tumors; and JANX008, an epidermal growth factor receptor that is in Phase 1 clinical trial for the treatment of various solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, renal cell carcinoma, small cell lung cancer, pancreatic ductal adenocarcinoma, and triple-negative breast cancer. Janux Therapeutics, Inc. has strategic research collaboration agreement with Merck Sharp & Dohme Corp. to develop TRACTr product candidates. The company was incorporated in 2017 and is headquartered in San Diego, California.