Janux Therapeutics Inc logo

Janux Therapeutics Inc(JANX)

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ADVISORIES YOU CAN VERIFY
QUALITY SIGNAL RECENCY
1-STAR RATING
SELL
SELL for 1 day
PROFIT SINCE LAST BUY
+8.01%
LAST CLOSE
$16.59
09/18/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
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Advisory Performance History (Simulated)Advisory Performance History info

Upturn Advisory & Investor View for JANX

09/18/2026: JANX (1-star) is a SELL. SELL for 1 day. Simulated Profits (8.01%). Updated daily EoD!

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Analysis of Past Performance

Type Stock
Historic Profit 41.46%
Avg. Invested days 33
Today’s Advisory SELL
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 2.0
Stock Returns Performance Upturn Returns Performance icon 3.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 09/18/2026

Upturn Scorecard

Upturn Star Rating

JANX receives a 3-star rating, supported by solid analyst coverage. The rating is constrained by soft unit economics, soft quantitative characteristics, and weak price momentum.

Company Fundamentals

JANX has moderate overall fundamentals (3 stars), with soft financial health, soft growth momentum, and solid ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-64.7%), soft cash generation (FCF margin -832.8%), negative revenue growth (-5.6%).

Financial Health Rating

JANX's financial health is supported by moderate liquidity, including working-capital and asset support (WC/assets 94.4%). Cash strength is soft (2 stars), which helps explain the 2-star overall score.

Growth Momentum Score

JANX's growth profile is soft, with the least-weak measure being revenue growth at -5.6% FY2025 versus FY2024. By comparison, while earnings growth (-64.7%, negative) and free-cash-flow growth (-88.5%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

Institutional ownership is 101.3% and approximately 69.6% of outstanding shares are publicly tradable, supporting liquidity and institutional participation. Insider ownership of 1.49% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

RA Capital Management, LLC 18.30%
BlackRock Inc 8.89%
HHG PLC 6.86%
Prosight Management, LP 6.22%
FMR Inc 4.15%

Unit Economics (Per $1K Revenue)

JANX generates approximately $797 of gross profit, $-15,767 of operating income, and $-8,328 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Strong cash conversion and healthy margins support the rating, although capital efficiency remains below the highest tier.

Economic Dimensions

Effective Tax Rate: 0.00%

Quantitative Style Profile

JANX has a liquid profile. Weak momentum is the primary drawback, while valuation that is moderately attractive rather than deeply discounted.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap RiskShort Squeeze RiskHighly Liquid / Institution-Friendly

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 1.03B USD
Price to earnings Ratio -
1Y Target Price 36.24
Price to earnings Ratio -
1Y Target Price 36.24
Volume (30-day avg) 906.9K shares
Beta 2.52
52 Weeks Range 12.12 - 35.34
Updated Date 09/18/2026
52 Weeks Range 12.12 - 35.34
Updated Date 09/18/2026
Dividends yield (FY) -
Basic EPS (TTM) -1.7
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Valuation

Trailing PE -
Forward PE -
Enterprise Value 43.24M
Price to Sales(TTM) 42.95
Enterprise Value 43.24M
Price to Sales(TTM) 42.95
Enterprise Value to Revenue 1.81
Enterprise Value to EBITDA -33.8
Shares Outstanding 61.14M
Shares Floating 42.53M
Shares Outstanding 61.14M
Shares Floating 42.53M
Percent Insiders 1.49
Percent Institutions 101.32

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

About Janux Therapeutics Inc

Exchange NASDAQ
Headquarters San Diego, CA, United States
IPO Launch date 2021-06-11
President, Co-Founder, CEO & Director Dr. David Alan Campbell Ph.D.
Sector Healthcare
Industry Biotechnology
Full time employees 113
Full time employees 113

Janux Therapeutics, Inc., a clinical stage biopharmaceutical company, develops immunotherapies based on Tumor Activated T Cell Engager (TRACTr), Tumor Activated Immunomodulator (TRACIr), and Adaptive Immune Response Modulator (ARM) platforms technology to treat patients with cancer. The company's clinical candidates include JANX007, a prostate-specific membrane antigen or PSMA-TRACTr, which is in Phase 1 clinical trial in adults for the treatment of metastatic castration-resistant prostate cancer and the vasculature of other tumors; and JANX008, an epidermal growth factor receptor that is in Phase 1 clinical trial for the treatment of various solid cancers, including colorectal cancer, squamous cell carcinoma of the head and neck, non-small cell lung cancer, renal cell carcinoma, small cell lung cancer, pancreatic ductal adenocarcinoma, and triple-negative breast cancer. It also develops JANX011, a CD19-targeted adaptive immune response modulator that is in phase 1 clinical study developed for autoimmune diseases. The company has strategic research collaboration agreement with Merck Sharp & Dohme Corp. to develop TRACTr product candidates; and Bristol Myers Squibb to develop and commercialize an undisclosed, novel tumor-activated therapeutic targeting a validated solid tumor antigen expressed across several human cancer types. Janux Therapeutics, Inc. was incorporated in 2017 and is headquartered in San Diego, California.