Transcode Therapeutics Inc logo

Transcode Therapeutics Inc(RNAZ)

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EXPLORE ADVISORIES AND THEIR HISTORY
QUALITY SIGNAL
1-STAR RATING
PASS
LAST CLOSE
$1.51
11/05/2026
(24-hour delay)

Advisory History & Simulated Performance *

*as per simulation (see disclosures)
  • ALL
  • 1Y
  • 1M
  • 1W
  • BUY Advisory
  • SELL Advisory (Profit)
  • SELL Advisory (Loss)
  • Profit
  • Loss
  • PASS (Skip)
Upturn Stock price based on last close iconStock price based on last close
Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Advisory Performance History (Simulated)Advisory Performance History info

Simulated performance—not actual client returns. Excludes advisory subscription fees, trading commissions, and taxes, which would reduce returns. Results depend on calculation assumptions and do not guarantee future outcomes. See Disclosures for full methodology, assumptions, and limitations.

Upturn Advisory & Investor View for RNAZ

11/05/2026: RNAZ (1-star) is currently NOT-A-BUY. Pass it for now.

Transcode Therapeutics is a clinical-stage biotechnology company developing RNA-based cancer treatments using its proprietary TTX delivery platform. The company's main strength lies in its innovative approach to overcoming RNA delivery challenges, which has led to a pipeline focused on metastatic cancer. Its investment story revolves around the potential clinical validation of the TTX platform, which could eventually yield transformative therapies. However, the company faces significant risks, including the absence of commercial revenue, high dependence on external financing, and the inherent uncertainty of clinical trials. It is best suited for speculative growth investors with a high risk tolerance who are closely monitoring clinical trial data and strategic partnership developments.

How to Read the Upturn Advisory

The Upturn Star Rating and the current BUY, SELL, or PASS advisory are generated by Upturn’s AI advisory engine based on proprietary signal analysis, price behavior, advisory history, and historical signal performance.

Company fundamentals, valuation, risks, and news provide supporting context about the business.

Investor Fit

Investor styleFitWhy
Growth investorMixed fitThis is a high-risk growth play that depends entirely on future clinical and regulatory success.
Momentum investorWeak fitMomentum is inconsistent and generally tied to binary clinical data outcomes rather than steady growth.
Value investorWeak fitThe company lacks current earnings or assets to support a traditional value-based investment thesis.
Dividend investorWeak fitThe company does not pay dividends and likely will not in the foreseeable future.
Low-risk investorWeak fitThe extreme volatility associated with pre-commercial biotech makes this unsuitable for low-risk portfolios.

Risk Profile

Risk factorLevelWhy it matters
Price volatilityHighThe stock is subject to extreme price swings based on clinical trial news.
Valuation riskHighValuation is speculative and based on the potential future success of early-stage assets.
Competition risk (RNA therapy competition)HighThe company faces immense competition from well-capitalized firms in the RNA space.
Business qualityLowThe company is in an early, pre-revenue stage without an established market footprint.
Dividend incomeLow / noneNo income potential exists for investors.
Execution riskHighFailure to advance clinical trials effectively would be catastrophic for the business.

Price Behavior

Steep Decline
PRICE PATH

Steep Decline

The stock price has dropped sharply with strong downward pressure.

Extreme Price Shocks
PRICE STABILITY

Extreme Price Shocks

The stock has experienced exceptionally large and disruptive price movements during the period.

Analysis of Past Performance

Type Stock
Historic Profit -84.51%
Avg. Invested days 9
Today’s Advisory PASS
Upturn Advisory Rating upturn star rating icon
Upturn Advisory Performance Upturn Advisory Performance icon 1.0
Stock Returns Performance Upturn Returns Performance icon 1.0
Upturn Profits based on simulation icon Profits based on simulation
Upturn last close icon Last Close 11/05/2026

Upturn Scorecard

Upturn Star Rating

★★★★★
RNAZ receives a 2-star rating, reflecting soft or weak scores across the available pillars. The rating is constrained by weak unit economics, soft company fundamentals, and soft quantitative characteristics.

Company Fundamentals

★★★★★
RNAZ has soft overall fundamentals (2 stars), with moderate financial health, soft growth momentum, and soft ownership. In FY2025 versus FY2024, growth and ownership metrics are mixed: negative earnings growth (-106.9%), soft cash generation (FCF margin 0.0%), slightly negative revenue growth (+0.0%).

Financial Health Rating

★★★★★
RNAZ's financial health is supported by strong efficiency, including operating-expense and cost-of-revenue discipline (opex 0.0% of revenue). Profitability is weak (1 stars), which helps explain the 3-star overall score.

Growth Momentum Score

★★★★★
RNAZ's growth profile is soft, with the least-weak measure being revenue growth at +0.0% FY2025 versus FY2024. By comparison, while earnings growth (-106.9%, negative) and free-cash-flow growth (-46.2%, negative) hold the profile back, so recent growth is not broad-based across the business.

Ownership

★★★★★
Institutional ownership is 0.4% (soft) and 12.7% of outstanding shares are publicly tradable (soft). Insider ownership of 1.78% provides only moderate management-shareholder alignment.

Top 5 Institutional Investors

Yorkville Advisors Global, LP 0.12%
Vanguard Capital Management, LLC 0.04%
Vanguard Fiduciary Trust Co 0.02%
UBS Group AG 0.02%
Mercer Global Advisors Inc. 0.01%

Unit Economics (Per $1K Revenue)

★★★★★
RNAZ generates approximately $-0 of gross profit, $-0 of operating income, and $-0 of free cash flow for every $1,000 of revenue. Based on FY2025 results. Weak margins explain the 1-star rating, with weak cash conversion and strong capital efficiency.

Economic Dimensions

★★★★★
Effective Tax Rate: -0.66% (Tax Credit)

Quantitative Style Profile

★★★★★
RNAZ has a High Volatility Profile profile. Weak momentum is the primary drawback, while elevated volatility.

Style Classification

Quality Focused

High VolatilitySmall / Mid Cap Risk

Key Highlights

Company Size Small-Cap Stock
Market Capitalization 27.09M USD
Price to earnings Ratio -
1Y Target Price 10
Price to earnings Ratio -
1Y Target Price 10
Volume (30-day avg) 29.7K shares
Beta 1.27
52 Weeks Range 1.48 - 12.60
Updated Date 11/05/2026
52 Weeks Range 1.48 - 12.60
Updated Date 11/05/2026
Dividends yield (FY) -
Basic EPS (TTM) -52.06

How Company Makes Money

Business areaWhat it includesRetail investor read
Clinical DevelopmentPotential future licensing or commercialization of RNA-based therapeutics.The company does not currently generate revenue and is spending money to test drugs.

Valuation

Trailing PE -
Forward PE -
Enterprise Value 184.73M
Price to Sales(TTM) -
Enterprise Value 184.73M
Price to Sales(TTM) -
Enterprise Value to Revenue -
Enterprise Value to EBITDA -0.59
Shares Outstanding 16.93M
Shares Floating 2.15M
Shares Outstanding 16.93M
Shares Floating 2.15M
Percent Insiders 1.78
Percent Institutions 0.44

Financial Metrics

🧭 Investment Snapshot

Total Revenue (Scale)

Information icon Total money earned from selling products or services before any costs. It is needed to understand the scale of the business and its ability to generate income.

Net Income (Profit)

Information icon Final profit after all expenses, interest, and taxes are deducted. It is needed to determine the overall profitability available to shareholders.

Free Cash Flow (Cash Strength)

Information icon Cash remaining after operating activities and capital expenditures, showing cash available for growth. It is needed to evaluate the company’s ability to invest, pay dividends, or reduce debt.

📈 Growth & Strength

Operating Income (Core Profit)

Information icon Profit from core operations after deducting all operating expenses. It is needed to measure how efficiently the company runs its primary business activities.

EBITDA (Cash Earnings)

Information icon Earnings before interest, taxes, depreciation, and amortization, indicating operating cash potential. It is needed to compare operating performance across companies without accounting or financing differences.

Gross Profit (Unit Profitability)

Information icon Revenue minus cost of revenue, showing profit after direct production costs. It is needed to evaluate core business profitability before overhead expenses.

🛡️ Financial Safety

Cash (Liquidity Buffer)

Information icon Total cash and cash equivalents on hand. It is needed to evaluate immediate liquidity and financial flexibility.

Total Debt (Leverage Risk)

Information icon Total debt including both short-term and long-term components. It is needed to assess the company’s leverage and financial risk.

Net Working Capital (Short-Term Health)

Information icon Current assets minus current liabilities, indicating short-term liquidity strength. It is needed to assess whether the company can meet its short-term obligations.

🧱 Balance Sheet Strength

Stockholder Equity (Net Worth)

Information icon Total equity value held by shareholders. It is needed to understand the net worth of the company from the owners’ perspective.

Total Assets (Asset Base)

Information icon The full value of everything the company owns, including cash, inventory, equipment, and investments. It is needed to understand the resource base used to generate revenue.

Income Before Tax (Pre-Tax Earnings)

Information icon Income before provision for income taxes. It is needed to analyze profitability independent of tax structures.

⚙️ Cost & Drag Factors

Cost of Revenue (Production Cost)

Information icon Direct costs required to produce and deliver the products or services sold. It is needed to assess efficiency in production and service delivery.

Total Operating Expenses (Operating Cost)

Information icon Indirect costs of running the business such as salaries, marketing, and administration. It is needed to understand how much it costs to sustain ongoing business operations.

Income Tax Expense (Tax Drag)

Information icon Amount of taxes paid or payable to the government. It is needed to evaluate the impact of taxation on overall profitability.

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