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Cardiol Therapeutics Inc Class A (CRDL)

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Upturn Advisory Summary
01/08/2026: CRDL (1-star) is currently NOT-A-BUY. Pass it for now.
1 Year Target Price $7.7
1 Year Target Price $7.7
| 1 | Strong Buy |
| 4 | Buy |
| 0 | Hold |
| 0 | Sell |
| 0 | Strong Sell |
Analysis of Past Performance
Type Stock | Historic Profit -19.19% | Avg. Invested days 31 | Today’s Advisory PASS |
Upturn Star Rating ![]() | Upturn Advisory Performance | Stock Returns Performance |
Key Highlights
Company Size Small-Cap Stock | Market Capitalization 101.00M USD | Price to earnings Ratio - | 1Y Target Price 7.7 |
Price to earnings Ratio - | 1Y Target Price 7.7 | ||
Volume (30-day avg) 5 | Beta 0.82 | 52 Weeks Range 0.77 - 1.59 | Updated Date 01/8/2026 |
52 Weeks Range 0.77 - 1.59 | Updated Date 01/8/2026 | ||
Dividends yield (FY) - | Basic EPS (TTM) -0.3 |
Earnings Date
Report Date - | When - | Estimate - | Actual - |
Profitability
Profit Margin - | Operating Margin (TTM) - |
Management Effectiveness
Return on Assets (TTM) -148.83% | Return on Equity (TTM) -347.98% |
Valuation
Trailing PE - | Forward PE - | Enterprise Value 93733085 | Price to Sales(TTM) 1069.35 |
Enterprise Value 93733085 | Price to Sales(TTM) 1069.35 | ||
Enterprise Value to Revenue 178.81 | Enterprise Value to EBITDA 0.3 | Shares Outstanding 99997648 | Shares Floating 84421008 |
Shares Outstanding 99997648 | Shares Floating 84421008 | ||
Percent Insiders 3.52 | Percent Institutions 11.24 |
Upturn AI SWOT
Cardiol Therapeutics Inc Class A
Company Overview
History and Background
Cardiol Therapeutics Inc. (TSX: CRDL) is a clinical-stage life sciences company focused on the development and commercialization of innovative treatments for cardiovascular disease. The company's primary focus is on its lead drug candidate, CRDL-002, a novel formulation of celecoxib. Significant milestones include advancing CRDL-002 through preclinical studies and initiating clinical trials.
Core Business Areas
- Therapeutics Development: Cardiol Therapeutics Inc. is primarily engaged in the research, development, and clinical testing of new drug candidates aimed at treating cardiovascular diseases. The company's pipeline is centered around CRDL-002, a proprietary formulation of celecoxib designed to reduce the inflammatory component of cardiovascular disease.
Leadership and Structure
Cardiol Therapeutics Inc. is led by a management team with experience in drug development and the pharmaceutical industry. The exact organizational structure is typical for a clinical-stage biotech company, with departments focused on research and development, clinical affairs, regulatory affairs, and business development.
Top Products and Market Share
Key Offerings
- Description: CRDL-002 is a proprietary, high-concentration formulation of celecoxib, a non-steroidal anti-inflammatory drug (NSAID). It is being developed for the treatment of chronic heart failure and other cardiovascular conditions by targeting inflammation. Market share data is not yet applicable as CRDL-002 is in clinical development. Competitors in the broader cardiovascular disease treatment market include companies developing various classes of drugs such as ACE inhibitors, beta-blockers, diuretics, and novel therapies targeting specific pathways.
- Product Name 1: CRDL-002
Market Dynamics
Industry Overview
The cardiovascular disease treatment market is a large and growing global industry, driven by an aging population, increasing prevalence of risk factors such as obesity and diabetes, and advancements in medical science. The market encompasses a wide range of therapeutic areas, from acute cardiac events to chronic management of conditions like heart failure and hypertension.
Positioning
Cardiol Therapeutics Inc. is positioning itself as a developer of novel anti-inflammatory therapies for cardiovascular diseases. Its focus on CRDL-002 aims to address a significant unmet need in managing the inflammatory component of these conditions. Its competitive advantage lies in its proprietary formulation and its potential to offer a differentiated therapeutic approach.
Total Addressable Market (TAM)
The total addressable market for cardiovascular disease treatments is in the hundreds of billions of dollars globally. Cardiol Therapeutics Inc. is currently targeting specific segments within this broad market, such as heart failure, which itself represents a substantial market opportunity. The company's positioning is focused on capturing a share of this TAM by demonstrating the efficacy and safety of its lead candidate in clinical trials.
Upturn SWOT Analysis
Strengths
- Proprietary drug formulation (CRDL-002) with potential for therapeutic differentiation.
- Focus on a significant unmet medical need in cardiovascular disease.
- Experienced management team with relevant industry expertise.
- Potential for intellectual property protection.
Weaknesses
- Clinical-stage company with no approved products.
- Reliance on successful clinical trial outcomes.
- Limited financial resources compared to larger pharmaceutical companies.
- Need for significant capital investment for further development and commercialization.
Opportunities
- Growing global prevalence of cardiovascular diseases.
- Potential for strategic partnerships or acquisitions by larger pharmaceutical companies.
- Advancements in understanding the role of inflammation in cardiovascular disease.
- Expansion into other cardiovascular indications.
Threats
- Failure to meet endpoints in clinical trials.
- Regulatory hurdles and lengthy approval processes.
- Competition from existing and emerging therapies.
- Changes in healthcare policy and reimbursement.
- Adverse events or safety concerns related to CRDL-002.
Competitors and Market Share
Key Competitors
- None publicly identified with definitive market share data in relation to CRDL-002's specific niche yet.
Competitive Landscape
The competitive landscape for CRDL-002 is still emerging as it progresses through clinical development. While celecoxib is an established NSAID, CRDL-002's novel formulation and intended application in cardiovascular disease aim to differentiate it. Competitors would include companies developing other anti-inflammatory agents or novel treatments for heart failure and related conditions.
Growth Trajectory and Initiatives
Historical Growth: Historical growth for Cardiol Therapeutics Inc. is primarily characterized by the progression of its drug candidate through the development pipeline, from preclinical research to clinical trials. Financial growth in terms of revenue is not yet a primary metric.
Future Projections: Future growth projections for Cardiol Therapeutics Inc. are contingent on the successful development and regulatory approval of CRDL-002. Analyst estimates, if available, would focus on potential peak sales post-commercialization, but these are speculative at this stage.
Recent Initiatives: Recent initiatives likely involve advancing CRDL-002 through its clinical trial phases, securing necessary regulatory approvals, and potentially exploring strategic partnerships for further development or commercialization.
Summary
Cardiol Therapeutics Inc. is a clinical-stage company with a promising drug candidate, CRDL-002, targeting cardiovascular diseases. Its strengths lie in its proprietary formulation and focus on an unmet medical need. However, it faces significant risks associated with clinical trial success and requires substantial capital. Future growth hinges on regulatory approval and market adoption, with potential threats from competition and unforeseen trial outcomes.
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Sources and Disclaimers
Data Sources:
- Company public filings (e.g., SEC filings, press releases)
- Financial data aggregators
- Industry research reports
Disclaimers:
This JSON output is for informational purposes only and does not constitute financial or investment advice. The data presented is based on publicly available information and may not be exhaustive or entirely accurate. Investors should conduct their own due diligence and consult with a qualified financial advisor before making any investment decisions.
AI Summarization is directionally correct and might not be accurate.
Summarized information shown could be a few years old and not current.
Fundamental Rating based on AI could be based on old data.
AI-generated summaries may have inaccuracies (hallucinations). Please verify the information before taking action.
About Cardiol Therapeutics Inc Class A
Exchange NASDAQ | Headquaters Oakville, ON, Canada | ||
IPO Launch date 2019-01-15 | President, CEO & Director Mr. David G. Elsley MBA | ||
Sector Healthcare | Industry Drug Manufacturers - Specialty & Generic | Full time employees 18 | Website https://www.cardiolrx.com |
Full time employees 18 | Website https://www.cardiolrx.com | ||
Cardiol Therapeutics Inc., a clinical-stage life sciences company, focuses on the developing of anti-fibrotic and anti-inflammatory therapies for the treatment of heart diseases. Its lead product candidate is CardiolRx, which is in Phase III multi-national, randomized, double-blind, and placebo-controlled study to evaluate the efficacy and safety of CardiolRx in acute myocarditis, as well as for the treatment of recurrent pericarditis. The company is also developing CRD-38 injection for subcutaneous administration that is in preclinical development for the treatment of heart failure. It has a license agreement with Meros. The company was incorporated in 2017 and is headquartered in Oakville, Canada.

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